Results 71 to 80 of about 14,924 (223)

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Food allergy in children with hypogammaglobulinemia

, 2012
IntroductionAntibody production defects may predispose children to inflammatory pathologies and therefore we hypothesized that this group of immune deficiencies may be associated with food allergy.Objective of the studyTo better characterize the ...
Lidia Ossowska, Szczawińska-Popłonyk, Aleksandra, Ossowska, Lidia, Bręborowicz, Anna, Aleksandra Szczawińska-Popłonyk, Anna Bręborowicz   +5 more
core   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Pure Red Cell Aplasia and Hypogammaglobulinemia in a Patient with Thymoma

, 2009
Both pure red cell aplasia (PRCA) and hypogammaglobulinemia are rarer conditions than myasthenia gravis (MG) in thymoma patients. Several articles have discussed the relation between PRCA and thymoma or hypogammaglobulinemia and thymoma, and their proper
Hsu, Wen-Hu, Lin, Chen-Sung, Yu, Yuan-Bin, Huang, Biing-Shiun, Chou, Teh-Ying, Hsu, Han-Shui   +5 more
core   +1 more source

Low immunoglobulin levels increase the risk of severe hypogammaglobulinemia in granulomatosis with polyangiitis patients receiving rituximab [PDF]

, 2016
Background: Randomized controlled trials and retrospective studies in ANCA-associated vasculitis (AAV) concurred that rituximab (RTX) is effective to induce and maintain remission.
Emilio Besada, Besada, Emilio
core   +1 more source

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

American Journal of Hematology, Volume 101, Issue 7, Page 1597-1604, July 2026.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo, Elisa Sambruna, Yoshitaka Miyakawa, Marc Michel, Carlo Visco, Michael Fillitz, George Kannourakis, Maria Bruna Greve, Moritz Kleemiss, Johan Cid, Andrea Patriarca, Laura Pavan, Arbana Dizdari, Nilla Maschio, Antonella Sau, Cinzia Bitetti, Riccardo Mario Colombo, Luigi Curreli, Dorela Lame, Uros Markovic, Fabrizio Pappagallo, Giacinto Luca Pedone, Davide Rapezzi, Vincenzo Sammartano, Nicola Tumedei, Antonio Giovanni Solimando, Jalink Marit, Luana Fianchi, Jahanzaib Khwaja, Antonio De Vivo, Francesco Lanza, Fabrizio Vianello, Esther N. Oliva, Catherine Broome, Francesco Passamonti, Ulrich Jaeger, Bernd Jilma, Guillaume Moulis, Wilma Barcellini   +38 more
wiley   +1 more source

Hypermobile type Ehlers‐Danlos syndrome associated with hypogammaglobulinemia and fibromyalgia: A case‐based review on new classification, diagnosis, and multidisciplinary management

Clinical Case Reports, 2019
Key Clinical Message Hypermobile type Ehlers‐Danlos syndrome (hEDS) is an underdiagnosed connective tissue disorder characterized by generalized joint hypermobility, chronic fatigue, widespread joints pain, and impaired quality of life. Here, we reported
Wei Zhang, Kevin Windsor, Richard Jones, David Oscar Taunton   +3 more
doaj   +1 more source

CAR‐T Cells in Ulcerative Colitis: The Renaissance of B‐Cell Targeted Therapy in UC

JCC Plus, Volume 1, Issue 4, July 2026.
ABSTRACT A recent New England Journal of Medicine report described the first successful use of anti‐CD19 CAR‐T cell therapy in a patient with multirefractory ulcerative colitis (UC). This exceptional case provides striking proof of concept that B cells and plasma cells can act as key pathogenic drivers in UC.
Zlata Chkolnaia, Mathieu Uzzan, Walter Reinisch   +2 more
wiley   +1 more source

B cell subsets reconstitution and immunoglobulin levels in children and adolescents with B non-Hodgkin lymphoma after treatment with single anti CD20 agent dose included in chemotherapeutic protocols: single center experience and review of the literature

Biomedical Papers
Background. RTX, an anti-CD20 monoclonal antibody, added to chemotherapy has proven to be effective in children and adolescents with high-grade, high-risk and matured non-Hodgkin lymphoma. RTX leads to prompt CD19+ B lymphocyte depletion.
Eva Hlavackova, Zdenka Krenova, Arpad Kerekes, Peter Slanina, Marcela Vlkova   +4 more
doaj   +1 more source

Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia

, 2023
Common variable immunodeficiency (CVID) is a rare disorder characterized by primary antibody deficiency leading to hypogammaglobulinemia and increased risk of infections.
Sara Limbiati, Girolamo Sala, Bellintani, Lorenzo, Fabrizio Foieni, Diana, Alessandro, Beatrice Valvo, Michela Provisione, Mariella Ciola, Zaza, Michele, Macchi, Federica, Roberto Bertolini, Federica Macchi, Limbiati, Sara, Paolo Ghiringhelli, Sala, Girolamo, Provisione, Michela, Valvo, Beatrice, Ciola, Mariella, Andrea Agostinelli, Agostinelli, Andrea, Bertolini, Roberto, Simoni, Cinzia, Alessandro Diana, Lorenzo Bellintani, Foieni, Fabrizio, Cinzia Simoni, Michele Zaza, Ghiringhelli, Paolo   +27 more
core   +1 more source