Results 121 to 130 of about 199,669 (336)

Multifaceted Study of Medicago marina Essential Oil: Chemical Composition, Antidiabetic, and Phytotoxic Insights via In Vitro and In Silico Approaches

Chemistry &Biodiversity, EarlyView.
ABSTRACT The essential oil of Medicago marina was subjected to analysis at vegetative and reproductive stages of development, with a particular emphasis on its chemical composition, α‐amylase inhibition, and allelopathic activities. The results of the gas chromatography and molecular docking studies demonstrated alterations in oil yield and composition
Marwa Melliti, Assia Hamdi, Mabrouk Horchani, Eliza de Jesus Barros dos Santos, Hichem Ben Jannet, Mohammad Faisal, Abdulrahman A. Alatar, Marcello Iriti, Mozaniel Santana de Oliveirae, Hayet Edziri   +9 more
wiley   +1 more source

Novel Insights Into the Bioactive Profile and Therapeutic Potentials of Indonesian Annona muricata Leaves

Chemistry &Biodiversity, EarlyView.
Pharmacological investigation of the aqueous extract of Annona muricata L. leaves from Indonesia. ABSTRACT This study investigates, for the first time, the comprehensive pharmacological profile of the aqueous extract of Annona muricata L. (graviola) leaves from Indonesia, focusing on its antioxidant, antinociceptive, and anti‐inflammatory properties ...
Sara Oufquir, Fatimazahra Agouram, Hamid Kabdy, Mehdi Ait Laaradia, Khadija Oubella, Baslam Abdelmoniim, Aboufatima Rachida, Stefania Garzoli, Abderrahman Chait   +8 more
wiley   +1 more source

Hypoglycemia Unawareness—A Review on Pathophysiology and Clinical Implications

Biomedicines
Hypoglycemia is a particular problem in people with diabetes while it can also occur in other clinical circumstances. Hypoglycemia unawareness describes a condition in which autonomic and neuroglycopenic symptoms of hypoglycemia decrease and hence are ...
Laura Hölzen, Bernd Schultes, Sebastian M. Meyhöfer, Svenja Meyhöfer   +3 more
doaj   +1 more source

Phenolic Compounds From Myrcia tijucensis: Insights Into Antioxidant and Antidiabetic Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT The genus Myrcia from the Myrtaceae family contains species with therapeutic properties, such as reducing glycemia and oxidative stress. This study investigated the effects of the hydroalcoholic extract of Myrcia tijucensis in an animal model of Type 1 diabetes induced by alloxan.
Nathielli Nayara Pauleti, Brenda Wiggers, Ana Luiza de Moraes G. Boaventura, Ana Carolina Dutra, Luiz Guilherme de Alcantara Grilo, Jan Pereira Wotmeyer, Camila Jeriane Paganelli, Camila Panini, Rafaela Beatriz Cunha, Michele Debiasi Alberton, Luciano Vitali, Gustavo Amadeu Micke, Daniela Delwing‐de Lima, Débora Delwing‐Dal Magro   +13 more
wiley   +1 more source

Rates of Hypoglycemia Predicted in Patients with Type 2 Diabetes on Insulin Glargine 300 U/ml Versus First- and Second-Generation Basal Insulin Analogs: The Real-World LIGHTNING Study [PDF]

, 2019
Jeremy Pettus, Ronan Roussel, Fang Liz Zhou, Zsolt Bosnyák, Jukka Westerbacka, Rachele Berria, Javier Jiménez, Björn Eliasson, Irene Hramiak, Timothy S. Bailey, Luigi Meneghini   +10 more
openalex   +1 more source

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

Chemistry &Biodiversity, EarlyView.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel, Ângela Liberal, Tiane C. Finimundy, Tânia S. P. Pires, Pedro Cravo, Maria Conceição Silva, Gustavo Capatti Cassiano, Lillian Barros, Maria M. Romeiras, Ângela Fernandes   +9 more
wiley   +1 more source

Successful Use of Octreotide Therapy for Refractory Levofloxacin-Induced Hypoglycemia: A Case Report and Literature Review

Case Reports in Critical Care, 2019
Fluoroquinolones are commonly prescribed antimicrobials that have been implicated in alterations of glucose metabolism. We report a case of refractory fluoroquinolone-induced hypoglycemia in a patient with type-2 diabetes mellitus on glipizide that was ...
Matthew R. Watson, Ceressa T. Ward, Amit Prabhakar, Babar Fiza, Vanessa Moll   +4 more
doaj   +1 more source

Small‐Molecule Sarco/Endoplasmic Reticulum Ca2+‐ATPase Activators Reverse Methylglyoxal‐Induced Inhibition through Nonantioxidant Mechanisms

ChemMedChem, EarlyView.
Endoplasmic reticulum (ER) Ca2+ dysregulation drives β‐cell dysfunction under diabetic stressors like methylglyoxal, which inhibits the sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) pump through oxidative modifications. We show that synthetic SERCA activators restore pump activity after methylglyoxal‐induced damage.
Carlos Cruz‐Cortés, Silvia Micháliková, Petronela Rezbáriková, L. Michel Espinoza‐Fonseca, Jana Viskupičová   +4 more
wiley   +1 more source

Hypoglycemia after Mitral Valve Repair in Dogs

Veterinary Sciences
Hypoglycemia has not been previously reported as a postoperative complication of mitral valve repair (MVR) in dogs; however, the authors have encountered cases of hypoglycemia after MVR. This study aimed to determine the incidence of hypoglycemia in dogs
Yasuyuki Nii, Emi Takahashi, Miho Tabata, Shimon Furusato, Masaya Katsumata, Masami Uechi   +5 more
doaj   +1 more source

QT Measurement and Heart Rate Correction during Hypoglycemia: Is There a Bias? [PDF]

, 2010
Toke Folke Christensen, Jette Randløv, Leif Engmann Kristensen, Ebbe Eldrup, Ole Hejlesen, Johannes J. Struijk   +5 more
openalex   +1 more source