Results 171 to 180 of about 197,099 (333)
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons +17 more
wiley +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man. [PDF]
A. J. Garber +5 more
openalex +1 more source
Neonatal seizures: Advances in diagnosis and management
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz +2 more
wiley +1 more source
The Effect of Adrenergic Blockade on the Glucagon Responses to Starvation and Hypoglycemia in Man [PDF]
Robert M. Walter +3 more
openalex +1 more source
Emerging green extraction techniques are revolutionizing the recovery of bioactive compounds from sweet potato (Ipomoea batatas [L.] Lam) leaves. These approaches enhance the yield and stability of key phytochemicals like caffeoylquinic acids, flavonoids, and polyphenols, which offer potent antioxidants, anti‐inflammatory, and metabolic health benefits.
M. H. A. Jahurul, S. Islam
wiley +1 more source

