Results 171 to 180 of about 102,857 (219)

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

Integrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang, Yonggang Niu, Shengkang Men, Yanghuilin Zhang, Xiaolong Tang, Kenneth B. Storey, Qiang Chen   +6 more
wiley   +1 more source

Relationship Between Hypoglycemia Frequency and Academic Performance in Children With Type 1 Diabetes. [PDF]

Cureus
Wazir KU, Naz H, Mahmood A, Ali P, Yar A, Imdad N, Mani Tripathi K, Mehboob AA.   +7 more
europepmc   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Development and validation of an interpretable machine learning model for predicting in-hospital hypoglycemia in adults with type 1 diabetes mellitus: a multicenter retrospective study. [PDF]

Front Endocrinol (Lausanne)
Zhang Q, Saad SH, Zhou H, Baakile BT, Fu Y, Li R, Han R, Tang Q, Xuan L, He G, Li H, Zhao Y, Zhu N, Zou J, Zhu X.   +14 more
europepmc   +1 more source

Evidence of a Protective Effect of Metformin on Abdominal Aortic Aneurysm Risk: Insights From an Observational Study and Mendelian Randomisation Analysis Using Putative Metformin Targets

Annals of Human Genetics, EarlyView.
ABSTRACT Aims There is no proven treatment to prevent the growth or rupture of abdominal aortic aneurysm (AAA). As an aneurysm enlarges over time, the risk of fatal aortic rupture increases. Metformin, a drug usually prescribed to treat Type 2 diabetes, has previously been associated with reduced AAA risk in observational studies. Our aim was to assess
Katie Louise Saxby, Svetlana Stoma, Frank Dudbridge, Nilesh J. Samani, Matthew J. Bown, Christopher P. Nelson   +5 more
wiley   +1 more source

Insulinoma after Roux-en-Y gastric bypass successfully treated by endoscopic ultrasound-guided radiofrequency ablation. [PDF]

JCEM Case Rep
Herrebout C, Bronswijk M, Maes T, Lefere M, Bourgain C, Ide V.   +5 more
europepmc   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

Clinical Presentation and Outcomes of Insulinomas in Pediatric Patients. [PDF]

Horm Res Paediatr
Mitteer LM, Sanchez-Kleinberg Y, Lord K, Sigal W, States LJ, Bhatti TR, Gallop RJ, Kelly A, Adzick NS, De Leon DD.   +9 more
europepmc   +1 more source

Genotype‐directed therapy for non–small cell lung cancer diagnosed during pregnancy: A pooled analysis of seven cases from the Cancer and Pregnancy Registry with maternal and neonatal outcomes and review of the literature

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this retrospective case series from a single database of pregnant women with cancer, seven were diagnosed with non‐small cell lung cancer (NSCLC). Chemotherapy and in some cases also biomarker‐directed therapy during pregnancy were associated with disease control allowing delivery closer to term and resulting in improved maternal outcomes compared ...
Reed Firestone, Elyce Cardonick
wiley   +1 more source