Results 71 to 80 of about 228,932 (402)

A study on the safety and efficacy of reveglucosidase alfa in patients with late-onset Pompe disease. [PDF]

, 2017
BackgroundLate-onset Pompe disease is a rare genetic neuromuscular disorder caused by lysosomal acid alpha-glucosidase (GAA) deficiency that ultimately results in mobility loss and respiratory failure.
Barohn, Richard, Barshop, Bruce A, Bratkovic, Drago, Byrne, Barry J, Desnuelle, Claude, Geberhiwot, Tarekegn, Haroldsen, Peter, Hughes, Derralynn, Jayaram, Kala, Laforet, Pascal, Mengel, Eugen, POM-001/002 Investigators, Reilley, Kristin, Roberts, Mark, Walsh, Liron, Yang, Ke   +15 more
core   +2 more sources

Severe hypoglycemia and risks of vascular events and death.

New England Journal of Medicine, 2010
BACKGROUND Severe hypoglycemia may increase the risk of a poor outcome in patients with type 2 diabetes assigned to an intensive glucose-lowering intervention.
S. Zoungas, Anushka Patel, J. Chalmers, B. D. de Galan, Qiang Li, L. Billot, M. Woodward, T. Ninomiya, B. Neal, S. MacMahon, D. Grobbee, A. Kengne, M. Marre, S. Heller   +13 more
semanticscholar   +1 more source

An auto-ethnographic study of co-produced health research in a patient organisation: unpacking the good, the bad, and the unspoken

Research Involvement and Engagement
Background In rare diseases, limited access to services and rare disease experts may force families to act as medical advocates for their child; they can volunteer to support clinician-initiated research or initiate and lead research themselves.
Astrid Janssens, Danielle Drachmann, Kristy Barnes-Cullen, Austin Carrigg, Henrik Thybo Christesen, Becky Futers, Yvette Ollada Lavery, Tiffany Palms, Jacob Sten Petersen, Pratik Shah, Paul Thornton, Joseph Wolfsdorf   +11 more
doaj   +1 more source

Living with hypoglycemia [PDF]

Journal of General Internal Medicine, 1998
To increase understanding of the everyday experiences of hypoglycemia for patients with type 1 diabetes through the use of a narrative research approach.Center for diabetes treatment and research.Cross-sectional assessment using a narrative research approach.Twenty outpatients (aged 21-30 years) diagnosed with type 1 diabetes for at least 10 years ...
Marilyn D. Ritholz, Alan M. Jacobson
openaire   +3 more sources

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, EarlyView.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

The changes in levels of blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction

Clinical and Experimental Dental Research, Volume 8, Issue 6, Page 1449-1455, December 2022., 2022
Abstract Objectives The extraction of a tooth exacerbates the stress in diabetic patients leading to diabetic complications so the aim was to evaluate the changes in blood cortisol, glucose, and oxygen saturation in type 2 diabetic patients during tooth extraction to pay special attention during a routine surgical procedure.
Zana Agani, Jehona Ahmedi, Resmije Ademi Abdyli, Mergime Prekazi Loxha, Vjosa Hamiti‐Krasniqi, Aida Rexhepi, David Stubljar   +6 more
wiley   +1 more source

The risk factors of inpatient hypoglycemia: A systematic review

Heliyon, 2020
Hypoglycemia is an important and harmful complication of Diabetes Mellitus (DM) that often occurs in inpatient or outpatient settings. Hypoglycemia can be divided into two types, i.e.
Chici Pratiwi, Muhammad Ikhsan Mokoagow, Ida Ayu Made Kshanti, Pradana Soewondo   +3 more
doaj  

Validation of ICD-9-CM coding algorithm for improved identification of hypoglycemia visits

BMC Endocrine Disorders, 2008
Background Accurate identification of hypoglycemia cases by International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes will help to describe epidemiology, monitor trends, and propose interventions for this important ...
Lieberman Rebecca M, Blanc Phillip G, Ginde Adit A, Camargo Carlos A   +3 more
doaj   +1 more source

Data-based modeling for hypoglycemia prediction: Importance, trends, and implications for clinical practice

Frontiers in Public Health, 2023
Background and objectiveHypoglycemia is a key barrier to achieving optimal glycemic control in people with diabetes, which has been proven to cause a set of deleterious outcomes, such as impaired cognition, increased cardiovascular disease, and mortality.
Liyin Zhang, Lin Yang, Zhiguang Zhou
doaj   +1 more source

Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 1 Diabetes: The SWITCH 1 Randomized Clinical Trial

Journal of the American Medical Association (JAMA), 2017
Importance Hypoglycemia, common in patients with type 1 diabetes, is a major barrier to achieving good glycemic control. Severe hypoglycemia can lead to coma or death.
Wendy Lane, T. Bailey, G. Gerety, J. Gumprecht, A. Philis-Tsimikas, C. T. Hansen, T. Nielsen, M. Warren   +7 more
semanticscholar   +1 more source