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Unawareness of Hypoglycemia by Insulin-Dependent Diabetics

Hormone and Metabolic Research, 1990
After several years of insulin therapy, about 20% of insulin-dependent diabetics have little or no perception of hypoglycaemia because of a loss of the adrenergic warning symptoms. This defect, poorly correlated with the presence of autonomic neuropathy, has been classically explained by a defect in the catecholamine secretion. We compared the hormonal
A, Grimaldi   +8 more
openaire   +2 more sources

SYMPTOMS OF HYPOGLYCEMIA, THRESHOLDS FOR THEIR OCCURRENCE, AND HYPOGLYCEMIA UNAWARENESS

Endocrinology and Metabolism Clinics of North America, 1999
Ultimately traceable to neural glucose deprivation, symptoms of hypoglycemia include neurogenic (autonomic) and neuroglycopenic symptoms. Neurogenic symptoms (tremulousness, palpitations, anxiety, sweating, hunger, paresthesias) are the results of the perception of physiologic changes caused by the autonomic nervous system's response to hypoglycemia ...
openaire   +2 more sources

Hypoglycemia and Hypoglycemia Unawareness During and Following Exercise

2012
Attention to diet, including meal composition and timing, is integral to all athletes’ training programs. Athletes with type 1 diabetes mellitus (type 1 DM) face the added task of administering insulin to carefully match energy availability and requirements.
Lisa M. Younk, Stephen N. Davis
openaire   +1 more source

Hypoglycemia-induced cognitive dysfunction in diabetes mellitus: Effect of hypoglycemia unawareness

Physiology & Behavior, 1995
Hypoglycemia results in cognitive dysfunction. The aim of this study was to assess and compare the degree of cognitive dysfunction experienced by insulin-dependent diabetic patients (IDDM) with hypoglycemia unawareness with patients with normal awareness of hypoglycemia.
A E, Gold   +3 more
openaire   +2 more sources

Reversal of Unawareness of Hypoglycemia

New England Journal of Medicine, 1993
Brain function depends on an adequate supply of glucose from the blood, and the principal danger of an inadequate supply is the loss of cognitive function.
openaire   +1 more source

Prevention and Management of Severe Hypoglycemia and Hypoglycemia Unawareness: Incorporating Sensor Technology

Current Diabetes Reports, 2018
In addition to assisting in achieving improved glucose control, continuous glucose monitoring (CGM) sensor technology may also aid in detection and prevention of hypoglycemia. In this paper, we report on the current scientific evidence on the effectiveness of this technology in the prevention of severe hypoglycemia and hypoglycemia unawareness.Recent ...
Paola, Lucidi   +3 more
openaire   +2 more sources

Effects of Hypoglycemia Unawareness on Exercise Management

Diabetes, 2018
Objective: Recent guidelines for management of T1D with exercise prompted us to determine if exercise management differs in T1D patients <15 yo with high or low hypoglycemia (hypo) awareness. Methods: 229 subjects or caretakers in a single academic practice completed a modified T1D Exchange questionnaire, describing hypo awareness
KRISTINA COSSEN   +2 more
openaire   +1 more source

The Contribution of Medications to Hypoglycemia Unawareness

Diabetes Spectrum, 2007
Hypoglycemia unawareness is defined as the onset of neuroglycopenia before the appearance of autonomic warning symptoms.1 It is difficult to study in its natural form because of its paroxysmal and unpredictable nature; therefore, well-controlled trials are limited.
openaire   +1 more source

Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM

Diabetes, 1994
To test the hypothesis that the neuroendocrine (including autonomic) responses to hypoglycemia are dissociated from the symptomatic responses to hypoglycemia in insulin-dependent diabetes mellitus (IDDM) patients with hypoglycemia awareness and during reversal of hypoglycemia unawareness in IDDM, we used the hyperinsulinemic stepped hypoglycemic (5.0 ...
S, Dagogo-Jack   +2 more
openaire   +2 more sources

Hypoglycemia, Hypoglycemia Unawareness and Counterregulation in Children and Adolescents with Type 1 Diabetes Mellitus

Journal of Pediatric Endocrinology and Metabolism, 2005
Three clinical phenomena have been defined in the last decade in patients with diabetes mellitus as a dangerous iatrogenic sequel of hypoglycemia. These are hypoglycemia unawareness, defective glucose counterregulation and a lowered hypoglycemic threshold for hypoglycemic symptoms.
Böber, Ece   +3 more
openaire   +5 more sources

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