Results 21 to 30 of about 2,746 (128)

Defective counterregulation and hypoglycemia unawareness in diabetes: mechanisms and emerging treatments. [PDF]

Endocrinol Metab Clin North Am, 2013
Reno CM, Litvin M, Clark AL, Fisher SJ.
europepmc   +3 more sources

Hypoglycemia Unawareness

Endocrine Reviews, 1991
Hypoglycemia unawareness can occur in diabetic as well as nondiabetic individuals. A single causative mechanism for its occurrence is not yet apparent. It is likely to be multifactorial but current evidence favors a major role for some type of CNS adaptation.
J E, Gerich, M, Mokan, T, Veneman, M, Korytkowski, A, Mitrakou   +4 more
openaire   +4 more sources

A Rare Case of Hypoglycemic Unawareness in a Patent With Chronic Congestve Heart Failure

Case Reports in Clinical Practice, 2019
Hypoglycemia and hypoglycemic unawareness is usually a complication of tight glycemic control in insulin-dependent diabetes mellitus. To our knowledge, this is the first case report of hypoglycemic unawareness subsequent to cardiac failure induced ...
Yawar Yaseen, Parvaiz Ahmad Shah, Irfan Mir, Saika Amreen   +3 more
doaj   +1 more source

Hypoglycemia Unawareness in IDDM

Diabetes Care, 1994
OBJECTIVE To assess the characteristics of patients with hypoglycemia unawareness (development of neuroglycopenia without appropriate prior autonomic warning symptoms) and its predisposing factors. RESEARCH DESIGN AND METHODS We studied 43 insulin ...
Mokan, M., Mitrakou, A., Veneman, T., Ryan, C., Korytkowski, M., Cryer, P., Gerich, J.   +6 more
openaire   +3 more sources

Asymptomatic Hyperinsulinaemic Hypoglycaemia

European Journal of Case Reports in Internal Medicine, 2020
Hypoglycaemia is rare in apparently well patients without drug-treated diabetes mellitus and warrants evaluation and management when Whipple’s triad is present.
Ana Ferreira, Mariana Serino Barbosa, Rita Coelho, Patrícia Lourenço   +3 more
doaj   +1 more source

High prevalence of depressive symptoms among people with pediatric‐onset and adolescent‐onset type 1 diabetes: A cross‐sectional analysis of the Diabetes Study from the Center of Tokyo Women's Medical University

Journal of Diabetes Investigation, 2022
Aims/Introduction To investigate the prevalence of depressive symptoms by the age of onset of type 1 diabetes, and its association with the condition of individuals with pediatric‐ and adolescent‐onset type 1 diabetes.
Hiroko Takaike, Junnosuke Miura, Kaya Ishizawa, Tetsuya Babazono   +3 more
doaj   +1 more source

Current and future therapies to treat impaired awareness of hypoglycemia

Frontiers in Pharmacology, 2023
In order to achieve optimal glycemic control, intensive insulin regimes are needed for individuals with Type 1 Diabetes (T1D) and insulin-dependent Type 2 Diabetes (T2D).
Erica L. Macon, Micah H. Devore, Yu Kuei Lin, Megan B. Music, Mason Wooten, Colleen A. McMullen, Andrea M. Woodcox, Ashlee R. Marksbury, Zachary Beckner, Bansi V. Patel, Lily A. Schoeder, Ashley N. Iles, Simon J. Fisher   +12 more
doaj   +1 more source

Hypoglycemic unawareness: challenges, triggers, and recommendations in patients with hypoglycemic unawareness: a case report

Journal of Medical Case Reports, 2022
Background Hypoglycemia is a fairly common complication in diabetic patients, particularly in those on insulin therapy. Hypoglycemia symptoms are classified into two types: autonomic and neuroglycopenic symptoms.
Yasaman Sharifi, Mahbube Ebrahimpur, Seyed Saeed Tamehrizadeh   +2 more
doaj   +1 more source

Ghrelin does not impact the blunted counterregulatory response to recurrent hypoglycemia in mice

Frontiers in Endocrinology, 2023
IntroductionRecurrent episodes of insulin-induced hypoglycemia in patients with diabetes mellitus can result in hypoglycemia-associated autonomic failure (HAAF), which is characterized by a compromised response to hypoglycemia by counterregulatory ...
Kripa Shankar, Salil Varshney, Deepali Gupta, Bharath K. Mani, Sherri Osborne-Lawrence, Nathan P. Metzger, Corine P. Richard, Jeffrey M. Zigman, Jeffrey M. Zigman, Jeffrey M. Zigman   +9 more
doaj   +1 more source

Reversibility of Unawareness of Hypoglycemia in Patients with Insulinomas

New England Journal of Medicine, 1993
A lack of appropriate autonomic warning symptoms before the development of neuroglycopenia occurs frequently in patients with diabetes mellitus. The pathogenesis of this phenomenon is unclear, but it is associated with intensive insulin therapy, prolonged duration of diabetes, frequent episodes of hypoglycemia, and impaired glucose counterregulation ...
Mitrakou A, FANELLI, Carmine Giuseppe, Veneman T, Perriello G, Calderone S, Platanisiotis D, Rambotti A, Raptis S, Brunetti P, Cryer P, Gerich J, BOLLI, Geremia Brunetto   +11 more
openaire   +4 more sources