A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System x\u3csub\u3ec\u3c/sub\u3e\u3csup\u3e−\u3c/sup\u3e Mediates Aglycemic Neuronal Cell Death [PDF]
, 2015 The astrocyte cystine/glutamate antiporter (system xc−) contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation. The purpose of this study was to determine the mechanism by which this occurred.
He, Yan +5 more
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Case of chronic indolent pheochromocytoma that caused medically controlled hypertension but treatment-resistant diabetes mellitus [PDF]
, 2017 No abstract ...
Cho, Eun Joo +4 more
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British Journal of Clinical Pharmacology, EarlyView.Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber +7 more
wiley +1 more source
Cognition and drug adherence to oral hypoglycemic and antihypertensive agents in older adults
Patient Preference and Adherence, 2019 Hamzah Bakouni,1,2 Lia Gentil,3 Helen-Maria Vasiliadis1–2,41Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada; 2Centre de recherche Charles-Le Moyne – Saguenay–Lac-Saint-Jean sur les ...
Bakouni H, Gentil L, Vasiliadis HM
doaj
Retrospective analysis reveals significant association of hypoglycemia with tramadol and methadone in contrast to other opioids. [PDF]
, 2019 Tramadol is one of the most commonly used analgesics worldwide, classified as having a low abuse potential by U.S. Drug Enforcement Agency, and often recommended in pain management guidelines.
Abagyan, Ruben +3 more
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Relationship of hyperglycaemia, hypoglycaemia, and glucose variability to atherosclerotic disease in type 2 diabetes [PDF]
, 2018 Objective: Type 2 diabetes mellitus (T2DM) is known to be associated with increased cardiovascular risk. The aim of this study was therefore to investigate the independent effects of hyperglycaemia, hypoglycaemia, and glucose variability on microvascular ...
Camilleri, Liberato +5 more
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BMEMat, EarlyView.The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang +6 more
wiley +1 more source
Research Progress in Bioactive Compounds in Medicine Food Homologous Plants for Intervention in Diabetes [PDF]
Shipin KexueDiabetes mellitus (DM) is a chronic, progressive systemic disease characterized by pancreatic β-cell dysfunction and insulin resistance. The primary symptom of this disease is elevated blood glucose levels. Medicine food homologous plants (MFP) contain a
ZHOU Yixia, QIN Luqi, DIAO Rao, ZHENG Jiahuan, LIU Jiameng, FAN Bei
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Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea
Chronic Diseases and Translational Medicine, EarlyView.Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy +3 more
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Human islet isolation and allotransplantation in 22 consecutive cases [PDF]
, 1992 This report provides our initial experience in islet isolation and intrahepatic allotransplantation in 21 patients. In group 1, 10 patients underwent combined liver-islet allotransplantation following upper-abdominal exenteration for cancer.
Alejandro, R +10 more
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