Results 71 to 80 of about 84,543 (289)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Antidiabetic effect of Psychotria malayana Jack in induced type 1 diabetic rat

Medisains, 2020
Background: Therapies for hyperglycemic treatment, including insulin and oral diabetes medications, have been confirmed to cause several side effects. Thus, finding new drugs with fewer side effects is of high importance.
Fairuz Fairuz, Hasna Dewi, Humaryanto Humaryanto   +2 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Research advances on the relationship between different hypoglycemic agents and acute kidney injury in type 2 diabetic patients

Linchuang shenzangbing zazhi
A rising incidence of acute kidney injury (AKI) may lead to longer hospitalization stays and even greater mortality. Diabetes is an independent risk factor for AKI and using hypoglycemic agents has been a fundamental glycemic control in diabetics ...
Dan-ning Guo, Meng-qing Ma, Chang-chun Cao   +2 more
doaj   +1 more source

A Review of the Anti-diabetic Activity of Andrographis Paniculata (Burm. F.) Nees Based In-vivo Study [PDF]

, 2015
Diabetes mellitus (DM) is ricing nowadays. DM is a metabolic deasease characterized by increasing of glucose blood level for prolonged time. Patient with DM must take medicine for lowering glucose levels in whole life.
Harimurti, S. (Sabtanti), Komalasari, T. (Titi)   +1 more
core  

Starvation of Cancer via Induced Ketogenesis and Severe Hypoglycemia

, 2014
Neoplasms are highly dependent on glucose as their substrate for energy production and are generally not able to catabolize other fuel sources such as ketones and fatty acids.
Kapelner, Adam, Vorsanger, Matthew
core   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Oral antidiabetic for the metabolic control in gestational diabetes

Acta Médica del Centro, 2016
The search for alternative therapies to insulin for the treatment of gestational diabetes goes back to studies from the decade of 1970 and 1980. The oral hypoglycemic agents have emerged as an effective alternative for metabolic control of gestational ...
Yoany Marín Tápanes, Sandi Jiménez Puñales   +1 more
doaj  

Ethnomedicinal survey of traditional antidiabetic plants in Baturraden and Sumbang

Medisains, 2020
Background: The scientific-based jamu development program enables the development of medicinal plants in the traditional medicine system that eventual-ly can be used in the formal healthcare system.
Wahyu Utaminingrum, Nofrianti Nofrianti, Dwi Hartanti   +2 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source