SIEDY Diagnostic Accuracy in Assessing Erectile Dysfunction in Young Men Living With HIV
ABSTRACT Background Erectile dysfunction (ED) is a multidimensional condition commonly affecting men living with HIV. The structured interview of erectile dysfunction (SIEDY) is the only validated tool assessing organic, relational, and psychological factors contributing to ED, while dynamic penile color Doppler ultrasound (dPCDU) is a reliable method ...
Giorgio Tiecco +10 more
wiley +1 more source
Testosterone deficiency in the aging male
Treatment for hypogonadism is on the rise, particularly in the aging population. Yet treatment in this population represents a unique challenge to clinicians.
J. Abram McBride +2 more
doaj +1 more source
Late-onset hypogonadism (LOH) : an emerging pathophysiological entity requiring the physician's attention [PDF]
Late-onset hypogonadism (LOH) is an emerging pathophysiological entity. Not everybody is familiar with LOH or even recognizes its existence. Since the 19th century women's life expectancy has become progressively greater than that of men and therefore ...
Nieschlag, Eberhard
core
Homozygous mutation in the prokineticin-receptor2 gene (Val274Asp) presenting as reversible Kallmann syndrome and persistent oligozoospermia: case report. [PDF]
Prokineticin 2 (Prok2) or prokineticin-receptor2 (Prok-R2) gene mutations are associated with Kallmann syndrome (KS). We describe a new homozygous mutation of Prok-R2 gene in a man displaying KS with an apparent reversal of hypogonadism.
Asci R +8 more
core +1 more source
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang +4 more
wiley +1 more source
Diagnosis and management of male hypogonadism in Germany
Background The extent to which male hypogonadism is diagnosed and treated remains ambiguous. This study scrutinizes the respective medical framework in Germany.Materials and methods This observational study retrospectively analyzes data from four million
Michael Zitzmann +4 more
doaj +1 more source
A Case of Hypogonadotropic Hypogonadism Caused by Opioid Treatment for Nonmalignant Chronic Pain
We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury.
Yukiko Tabuchi +12 more
doaj +1 more source
Normosmic idiopathic hypogonadotrophic hypogonadism due to a rare KISS1R gene mutation
Hypogonadotrophic hypogonadism is due to impaired or reduced gonadotrophin secretion from the pituitary gland. In the absence of any anatomical or functional lesions of the pituitary or hypothalamic gland, the hypogonadotrophic hypogonadism is referred ...
N Chelaghma, S O Oyibo, J Rajkanna
doaj +1 more source
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]
Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
core +1 more source
Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 Oxidoreductase deficiency [PDF]
Context: P450 oxidoreductase (POR) is a crucial electron donor to all microsomal P450 cytochrome (CYP) enzymes including 17α-hydroxylase (CYP17A1), 21-hydroxylase (CYP21A2) and P450 aromatase.
Adachi +59 more
core +2 more sources

