Results 81 to 90 of about 57,268 (271)

When is a varicocele repair indicated: the dilemma of hypogonadism and erectile dysfunction?

open access: yesAsian Journal of Andrology, 2016
In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain.
Ali A Dabaja, Marc Goldstein
doaj   +1 more source

Contact Activation Is Alleviated by Testosterone Replacement Therapy in Klinefelter Syndrome: Evidence of Hormonal and Metabolic Modulation

open access: yesAndrology, EarlyView.
ABSTRACT Background Klinefelter syndrome is associated with a markedly increased risk of venous thrombosis. While hypogonadism and metabolic dysfunction are known contributors, the role of the contact activation system in Klinefelter syndrome remains unexplored.
Simon Chang   +4 more
wiley   +1 more source

Late-onset hypogonadism: beyond testosterone

open access: yes, 2015
Late-onset hypogonadism is defined as a combination of low testosterone (T) levels and typical symptoms and signs. A major area of uncertainty is whether T concentrations are always really sufficient to fully reflect Leydig cell (dys)function.
FERLIN, ALBERTO
core   +2 more sources

Normosmic idiopathic hypogonadotrophic hypogonadism due to a rare KISS1R gene mutation

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2018
Hypogonadotrophic hypogonadism is due to impaired or reduced gonadotrophin secretion from the pituitary gland. In the absence of any anatomical or functional lesions of the pituitary or hypothalamic gland, the hypogonadotrophic hypogonadism is referred ...
N Chelaghma, S O Oyibo, J Rajkanna
doaj   +1 more source

Clinical and Hormonal Profile of Hypogonadism [PDF]

open access: yes, 2009
SUMMARY: Hypogonadism is an important problem with which many boys and girls present to the Endocrine out patient aepartment. They experience significant emotional problems due to their reduced secondary sexual characters and delayed puberty.
Jegan Niwas, K
core  

Male Central Hypogonadism in Paediatrics - the Relevance of Follicle-stimulating Hormone and Sertoli Cell Markers [PDF]

open access: yes, 2018
The definition of male hypogonadism used in adult endocrinology is not fully applicable to paediatrics. A clear understanding of the developmental physiology of the hypothalamic-pituitary-testicular axis is essential for the comprehension of the ...
Grinspon, Romina   +2 more
core   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

open access: yesAndrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan   +10 more
wiley   +1 more source

Testosterone deficiency in the aging male

open access: yesTherapeutic Advances in Urology, 2016
Treatment for hypogonadism is on the rise, particularly in the aging population. Yet treatment in this population represents a unique challenge to clinicians.
J. Abram McBride   +2 more
doaj   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

open access: yesAndrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben   +3 more
wiley   +1 more source

Diagnosis and terminology in hypogonadism

open access: yes, 2022
Hypogonadism (testosterone deficiency) is a clinical and biochemical syndrome that stems from a reduced production of testosterone and sperm cells by the testis.
Schartau, Patricia ES
core   +1 more source

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