Results 81 to 90 of about 53,137 (275)

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Clinical and Hormonal Profile of Hypogonadism [PDF]

, 2009
SUMMARY: Hypogonadism is an important problem with which many boys and girls present to the Endocrine out patient aepartment. They experience significant emotional problems due to their reduced secondary sexual characters and delayed puberty.
Jegan Niwas, K
core  

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Late-onset hypogonadism: beyond testosterone

, 2015
Late-onset hypogonadism is defined as a combination of low testosterone (T) levels and typical symptoms and signs. A major area of uncertainty is whether T concentrations are always really sufficient to fully reflect Leydig cell (dys)function.
FERLIN, ALBERTO
core   +2 more sources

Use of testosterone replacement therapy to treat long-COVID-related hypogonadism

Endocrinology, Diabetes & Metabolism Case Reports
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can impair pituitary–gonadal axis and a higher prevalence of hypogonadism in post-coronavirus disease 2019 (COVID-19) patients compared with the general population has been highlighted. Here we
Alessandro Amodeo, Luca Persani, Marco Bonomi, Biagio Cangiano   +3 more
doaj   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Diagnosis and management of male hypogonadism in Germany

The Aging Male
Background The extent to which male hypogonadism is diagnosed and treated remains ambiguous. This study scrutinizes the respective medical framework in Germany.Materials and methods This observational study retrospectively analyzes data from four million
Michael Zitzmann, Diethe Ortius-Lechner, Nadine Thierfelder, Christian Schindler, Dennis Häckl   +4 more
doaj   +1 more source

Testosterone deficiency in the aging male

Therapeutic Advances in Urology, 2016
Treatment for hypogonadism is on the rise, particularly in the aging population. Yet treatment in this population represents a unique challenge to clinicians.
J. Abram McBride, Culley C. Carson, Robert M. Coward   +2 more
doaj   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

When is a varicocele repair indicated: the dilemma of hypogonadism and erectile dysfunction?

Asian Journal of Andrology, 2016
In the past, the indications for varicocelectomy are primarily for infertility with abnormal semen parameters, testicular hypotrophy/atrophy in adolescents, and/or pain.
Ali A Dabaja, Marc Goldstein
doaj   +1 more source