Results 71 to 80 of about 53,350 (292)

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Association Between Type 2 Diabetes and Hypogonadism in India: An Observational Study

Indian Journal of Endocrinology and Metabolism
Introduction: Hypogonadism is a common comorbidity associated with several metabolic disorders including type 2 diabetes (T2D) that can remain undetected without proper screening.
Ambika G. Unnikrishnan, Banshi D. Saboo, Anirban Majumdar, Ravi K. Saraogi, Shanmuga Sundar, Shriraam Mahadevan, Anantharaman Ramakrishnan, Indraneel Basu, Deep Dutta, Arpan D. Bhattacharya, Prakadeesh Bharathi, Kalpesh Gawand   +11 more
doaj   +1 more source

Guidelines for the Diagnosis and Treatment of testosterone deficiency (hypogonadism) in male patients with diabetes mellitus

Ожирение и метаболизм, 2017
Hypogonadism in men, defined as a reduction in serum testosterone in combination with characteristic symptoms and/or signs (described in detail later), is common in diabetes mellitus (DM). These recommendations do not cover the whole range of pathologies
Ivan I. Dedov, Galina A. Mel'nichenko, Marina V. Shestakova, Roman V. Rozhivanov, Anna L. Terehova, Alexey V. Zilov, Daria O. Ladygina, Dmitriy G. Kurbatov   +7 more
doaj   +1 more source

Diagnosis and terminology in hypogonadism [PDF]

, 2022
Hypogonadism (testosterone deficiency) is a clinical and biochemical syndrome that stems from a reduced production of testosterone and sperm cells by the testis.
Schartau, Patricia ES
core  

Late-onset Hypogonadism: bone health. [PDF]

, 2020
Background: Bone health is underdiagnosed and undermanaged in men. Bone loss occurs in men with hypogonadism and in aging men. Thus, patients with a diagno- sis of late-onset hypogonadism (LOH) are at risk of osteoporosis and osteoporotic fractures ...
Rochira
core   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Selective estrogen receptor modulators and aromatase inhibitors in the treatment of functional male hypogonadism

Endokrynologia Polska
Functional hypogonadism is a syndrome characterized by low testosterone levels and clinical features of hypogonadism without organic disease of the hypothalamus–pituitary–gonadal axis.
Jakub Wydra, Arnika Wydra, Piotr Kucharczyk, Grzegorz Kapuściński, Wojciech Zgliczyński, Michał Rabijewski   +5 more
doaj   +1 more source

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

Andrology, EarlyView.
Abstract Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier, Jann‐Frederik Cremers, Phillip Schrage, Amelie Körtje, Claudia Krallmann, Sabine Kliesch, Jörg Gromoll, Sandra Laurentino, Michael Zitzmann   +8 more
wiley   +1 more source

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Nasal delivery of nerve growth factor rescue hypogonadism by up-regulating GnRH and testosterone in aging male miceResearch in context

EBioMedicine, 2018
Background: Nerve growth factor (NGF) plays essential roles in regulating the development and maintenance of central sympathetic and sensory neurons. However, the effects of NGF on hypogonadism remain unexplored.
Jiao Luo, Yan Yang, Tiantian Zhang, Zhijian Su, Dan Yu, Qilian Lin, Haolin Chen, Qihao Zhang, Qi Xiang, Wei Xue, Renshan Ge, Yadong Huang   +11 more
doaj   +1 more source