Results 61 to 70 of about 57,268 (271)

Hypogonadism in Systemic Diseases

, 2017
Serum testosterone is often lower than normal in patients with acute or chronic systemic diseases. The underlying mechanisms involved in the reduced testosterone secretion depend on the type of systemic disease; thus, many pathogenetic mechanisms might ...
ROCHIRA, Vincenzo, Vincenzo Rochira
core   +1 more source

Genetics of congenital central hypogonadism

, 2022
The diagnostic suspicion of congenital central hypogonadism is based on clinical signs. Biochemical confirmation is challenging, especially after the postnatal activation stage of the hypothalamic–pituitary–testicular axis. Sertoli cell markers, like AMH
Grinspon, Romina
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

MINERAL METABOLISM AND BONE MINERAL DENSITY IN PATIENTS WITH CENTRAL HYPOGONADISM AS INDICATORS OF PREMATURE AGING

Остеопороз и остеопатии, 2015
Aim of this study was to estimate the markers of mineral turnover and BMD in young women with the central hypogonadism, to compare them with healthy young women and healthy postmenopausal women of middle/advanced age. Materials and methods.
I A Ilovaiskaya, L B Lazebnik, V Yu Zektser, A V Dreval, G A Melnichenko   +4 more
doaj   +1 more source

Management of hypogonadism from birth to adolescence. [PDF]

, 2018
Management of patients with hypogonadism is dependent on the underlying cause. Whilst functional hypogonadism presenting as delayed puberty in adolescence is relatively common, permanent hypogonadism presenting in infancy or adolescence is unusual.
Sasha R. Howard, Leo Dunkel, Howard, SR, Dunkel, L   +3 more
core   +1 more source

Potential Neuroendocrine Disruption by Benzodiazepines and Its Impact on Male Fertility

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neuroactive substances have emerged as potent endocrine disruptors affecting male reproductive health through central and peripheral mechanisms. Among these, benzodiazepines, which are widely used for the management of anxiety, insomnia, epilepsy, and neuromuscular disorders, are known as GABA A (gamma‐aminobutyric acid type A) receptor ...
Ana Clara Melo Andrade de Rodrigues, Julia Gonçalves Rodrigues, Marcos de Lucca Moreira Gomes, Fernanda Carolina Ribeiro Dias   +3 more
wiley   +1 more source

Prevalence of Hypogonadism and Associated Risk Factors among Newly Diagnosed ART Naïve HIV-Infected Males in Mwanza, Tanzania

International Journal of Endocrinology
Background. Hypogonadism is frequent among HIV-infected males and might have significant clinical impact leading to sexual impairment and metabolic derangement.
Shabani Iddi, Haruna Dika, Benson Kidenya, Samuel Kalluvya   +3 more
doaj   +1 more source

Treatment of male hypogonadism partially reverses oxidative stress in patients with hypogonadism

, 2020
There are some studies regarding the presence/absence of oxidative stress in patients with hypogonadism with limited number of parameters. We aimed to investigate the effects of male hypogonadism and its treatment on oxidative stress parameters. Thirteen
Sik, Sevil Kaya, BARLAK KETİ, DİDEM, Kose, Kader, ÜNLÜHİZARCI, KÜRŞAD, Karaca, ZÜLEYHA CİHAN, HACIOĞLU, AYŞA   +5 more
core   +1 more source

Long‐term clinical trajectory of microvillus inclusion disease associated with STXBP2‐related familial hemophagocytic lymphohistiocytosis type 5: A case report

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Familial hemophagocytic lymphohistiocytosis type 5 is caused by biallelic pathogenic variants in STXBP2, which encodes syntaxin‐binding protein, a key regulator of vesicle trafficking. In addition to immune dysregulation, patients with familial hemophagocytic lymphohistiocytosis type 5 may present with severe, persistent diarrhea associated ...
Hiroyuki Tanaka, Mariko Sekiguchi, Yuko Kajiho, Tetsuo Ushiku, Jun Fujishiro, Motohiro Kato   +5 more
wiley   +1 more source

Mixed Hypogonadism: A New Type of Hypogonadism

, 2023
Abstract Purpose Kallmann syndrome is a rare disease characterized by delayed puberty, infertility and anosmia. We report the clinical and genetic characteristics of four patients with Kallmann syndrome who presented with Klinefelter syndrome or primary testicular disease and defined a new type of hypogonadism as mixed hypogonadism.
xueyan wu, Rui Zhang, Bingqing Yu, Xi Wang, Min Nie, Wanlu Ma, Wen Ji, Qibin Huang, Yiyi Zhu, Bang Sun, Junyi Zhang, Wei Zhang, Hongying Liu, Jiangfeng Mao   +13 more
openaire   +1 more source