Results 61 to 70 of about 53,137 (275)

Polymerized Pro‐Estrogen Microneedles via Two Photon Polymerization

Macromolecular Rapid Communications, EarlyView.
Acrylic pro‐drugs of 17β‐estradiol were subjected to spatially controlled two‐photon polymerization to create bespoke microneedle geometries with potential biomedical applications for long‐term transdermal hormone delivery. ABSTRACT Two‐photon polymerization (TPP) is a powerful technique to create microscale structures with high precision, offering ...
Yang Lou, John T. Leman, Harper Serringer, Ke Xia, Christopher N. LaFratta, Chaitanya Ullal, Edmund F. Palermo   +6 more
wiley   +1 more source

Hypogonadism and associated factors among male Leprosy patients.

PLoS Neglected Tropical Diseases
BackgroundLeprosy affects various organs in addition to skin, eyes, and peripheral nerves. Testicular involvement in leprosy patients is common and causes disturbance in endocrine function of the testis and results in hypogonadism.
Nafyad Tolossa Urgie, Miftah Oumer Surur, Shimelis Nigussie, Beniam Worku Yigazu, Kidist Bobosha, Abebaye Aragaw, Getahun Shibru   +6 more
doaj   +1 more source

Association Between Type 2 Diabetes and Hypogonadism in India: An Observational Study

Indian Journal of Endocrinology and Metabolism
Introduction: Hypogonadism is a common comorbidity associated with several metabolic disorders including type 2 diabetes (T2D) that can remain undetected without proper screening.
Ambika G. Unnikrishnan, Banshi D. Saboo, Anirban Majumdar, Ravi K. Saraogi, Shanmuga Sundar, Shriraam Mahadevan, Anantharaman Ramakrishnan, Indraneel Basu, Deep Dutta, Arpan D. Bhattacharya, Prakadeesh Bharathi, Kalpesh Gawand   +11 more
doaj   +1 more source

Pathophysiology and Clinical Manifestations of Hypogonadism

, 2023
Hypogonadism is a condition where the function of the gonad glands decreases, resulting in a decrease in hormone levels due to the hypothalamus-pituitary-gonad (HPG) axis. Hypogonadism occurs in approximately 2.1% – 12.8% of the middle-aged to older male
Duarsa, Ni Made Meta Satya Buda, Triani, Eva, Khalda, Yumna Iftinan, Purnama, Ranti Filarma Negara, Nurma'rifatullah   +4 more
core  

Rare Chromosomal Variants in Males with Hypogonadism: A Case Series From Tertiary Hospital in India

National Board of Examinations Journal of Medical Sciences
Male hypogonadism refers to decrease in testosterone levels due to diminished activity of testes. Hypogonadism will result in infertility, absent or poor secondary sexual characteristics and abnormal genitalia.
Anjali Shastry
doaj   +1 more source

Testosterone Versus Clomiphene Treatment of Hypogonadism: A Retrospective Analysis in US Veterans. [PDF]

Andrology
ABSTRACT Background Male hypogonadotropic hypogonadism is a complex condition with a multifactorial etiology. Although testosterone replacement therapy (TRT) is the only approved treatment for male hypogonadism, clomiphene citrate (CC) is often used as an off‐label treatment.
Tadisina S, Cristiano E, Wiegmann T, Grasing K, Drees B, Sharma R, Garcia-Touza M.   +6 more
europepmc   +2 more sources

Mixed Hypogonadism: A New Type of Hypogonadism

, 2023
Abstract Purpose Kallmann syndrome is a rare disease characterized by delayed puberty, infertility and anosmia. We report the clinical and genetic characteristics of four patients with Kallmann syndrome who presented with Klinefelter syndrome or primary testicular disease and defined a new type of hypogonadism as mixed hypogonadism.
xueyan wu, Rui Zhang, Bingqing Yu, Xi Wang, Min Nie, Wanlu Ma, Wen Ji, Qibin Huang, Yiyi Zhu, Bang Sun, Junyi Zhang, Wei Zhang, Hongying Liu, Jiangfeng Mao   +13 more
openaire   +1 more source

Late-onset Hypogonadism: bone health. [PDF]

, 2020
Background: Bone health is underdiagnosed and undermanaged in men. Bone loss occurs in men with hypogonadism and in aging men. Thus, patients with a diagno- sis of late-onset hypogonadism (LOH) are at risk of osteoporosis and osteoporotic fractures ...
Rochira
core   +1 more source

Long‐Term Outcomes of Deep Brain Stimulation in Woodhouse–Sakati Syndrome

Movement Disorders, EarlyView.
Abstract Background Woodhouse–Sakati syndrome (WSS) is a rare autosomal recessive disease with distinctive neuroendocrine manifestations, with dystonia being the most common. No clear guidelines are available for the treatment of dystonia in WSS. Objective The aim was to analyze the impact of deep brain stimulation (DBS) on WSS‐associated dystonia ...
Hend Alhodaif, Yara Alkhodair, Faisal Alotaibi, Salma Alqahtani, Saeed Bohlega, Amaal Aldakheel   +5 more
wiley   +1 more source

Guidelines for the Diagnosis and Treatment of testosterone deficiency (hypogonadism) in male patients with diabetes mellitus

Ожирение и метаболизм, 2017
Hypogonadism in men, defined as a reduction in serum testosterone in combination with characteristic symptoms and/or signs (described in detail later), is common in diabetes mellitus (DM). These recommendations do not cover the whole range of pathologies
Ivan I. Dedov, Galina A. Mel'nichenko, Marina V. Shestakova, Roman V. Rozhivanov, Anna L. Terehova, Alexey V. Zilov, Daria O. Ladygina, Dmitriy G. Kurbatov   +7 more
doaj   +1 more source