Pituitary imaging findings in pediatric patients with idiopathic hypogonadotropic hypogonadism
Objective. Idiopathic hypogonadotropic hypogonadism in children is a disease leading to a puberty absence. Some hypothalamic and pituitary defects cause hypogonadotropic hypogonadism.
Bitkin Eda Celebi +2 more
doaj +1 more source
Building families—Implementing balanced sexual and reproductive health
Abstract One of the main initiatives of the World Health Organization (WHO) is the promotion of Sexual and Reproductive Health (SRH). Sexuality, infertility, and contraception are three interconnected pillars of SRH, each essential for achieving global equity in family planning and family building.
Peter Y. Liu +9 more
wiley +2 more sources
A Current Perspective on Delayed Puberty and Its Management
Delayed puberty is defined as the lack of development of secondary sex characteristics in childhood. Based on a review of the literature, delayed puberty can be divided into three main categories: (i) hypergonadotropic hypogonadism (congenital and ...
Ayhan Abacı, Özge Besci
doaj +1 more source
Pathophysiology and Clinical Manifestations of Hypogonadism [PDF]
Hypogonadism is a condition where the function of the gonad glands decreases, resulting in a decrease in hormone levels due to the hypothalamus-pituitary-gonad (HPG) axis. Hypogonadism occurs in approximately 2.1% – 12.8% of the middle-aged to older male
Duarsa, Ni Made Meta Satya Buda +4 more
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Jacobs Syndrome Presenting With Delayed Puberty and Central Hypogonadism: A Rare Case Report. [PDF]
ABSTRACT In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
Javaid MH +4 more
europepmc +2 more sources
Metabolic status and hypogonadism in human immunodeficiency virus-infected males
Aims and Objectives: The aim of this study is to determine the prevalence of hypogonadism in human immunodeficiency virus (HIV)-infected males and to study its relation to age, CD4 count, body mass index (BMI), duration of highly active antiretroviral ...
Sarita Bajaj +3 more
doaj +1 more source
Clinical case seminar - Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita [PDF]
Mutations in the orphan nuclear receptor DAX-1 cause X-linked adrenal hypoplasia congenita. Affected boys usually present with primary adrenal failure in early infancy or childhood.
Beck-Peccoz, P +8 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Hypogonadism in male patients is defined as a decrease in the serum testosterone level; it is associated with specific symptoms and/or signs (see the detailed description below). It is a common complication in diabetes mellitus.
Galina Afanas'evna Melnichenko +6 more
doaj +1 more source
Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay [PDF]
Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Meeks, JJ +12 more
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