Results 41 to 50 of about 57,268 (271)

Pituitary imaging findings in pediatric patients with idiopathic hypogonadotropic hypogonadism

open access: yesEndocrine Regulations, 2023
Objective. Idiopathic hypogonadotropic hypogonadism in children is a disease leading to a puberty absence. Some hypothalamic and pituitary defects cause hypogonadotropic hypogonadism.
Bitkin Eda Celebi   +2 more
doaj   +1 more source

Building families—Implementing balanced sexual and reproductive health

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract One of the main initiatives of the World Health Organization (WHO) is the promotion of Sexual and Reproductive Health (SRH). Sexuality, infertility, and contraception are three interconnected pillars of SRH, each essential for achieving global equity in family planning and family building.
Peter Y. Liu   +9 more
wiley   +2 more sources

A Current Perspective on Delayed Puberty and Its Management

open access: yesJCRPE
Delayed puberty is defined as the lack of development of secondary sex characteristics in childhood. Based on a review of the literature, delayed puberty can be divided into three main categories: (i) hypergonadotropic hypogonadism (congenital and ...
Ayhan Abacı, Özge Besci
doaj   +1 more source

Pathophysiology and Clinical Manifestations of Hypogonadism [PDF]

open access: yes, 2023
Hypogonadism is a condition where the function of the gonad glands decreases, resulting in a decrease in hormone levels due to the hypothalamus-pituitary-gonad (HPG) axis. Hypogonadism occurs in approximately 2.1% – 12.8% of the middle-aged to older male
Duarsa, Ni Made Meta Satya Buda   +4 more
core  

Jacobs Syndrome Presenting With Delayed Puberty and Central Hypogonadism: A Rare Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT In some rare instances, patients with 47,XYY syndrome can be short in height, accompanied by hypogonadism without the characteristic tall stature. In cases where there is delayed puberty and unusual growth pattern, a complete endocrine work‐up, including GnRH and hCG stimulation tests, along with chromosome studies, is vital.
Javaid MH   +4 more
europepmc   +2 more sources

Metabolic status and hypogonadism in human immunodeficiency virus-infected males

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
Aims and Objectives: The aim of this study is to determine the prevalence of hypogonadism in human immunodeficiency virus (HIV)-infected males and to study its relation to age, CD4 count, body mass index (BMI), duration of highly active antiretroviral ...
Sarita Bajaj   +3 more
doaj   +1 more source

Clinical case seminar - Hypogonadotropic hypogonadism as a presenting feature of late-onset X-linked adrenal hypoplasia congenita [PDF]

open access: yes, 2002
Mutations in the orphan nuclear receptor DAX-1 cause X-linked adrenal hypoplasia congenita. Affected boys usually present with primary adrenal failure in early infancy or childhood.
Beck-Peccoz, P   +8 more
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Guidelines for the diagnosis and treatment of testosterone deficiency (hypogonadism) in male patients with diabetes mellitus (Draft)

open access: yesСахарный диабет, 2017
Hypogonadism in male patients is defined as a decrease in the serum testosterone level; it is associated with specific symptoms and/or signs (see the detailed description below). It is a common complication in diabetes mellitus.
Galina Afanas'evna Melnichenko   +6 more
doaj   +1 more source

Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay [PDF]

open access: yes, 1999
Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Meeks, JJ   +12 more
core  

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