Progressive onset of adrenal insufficiency and hypogonadism of pituitary origin caused by a complex genetic rearrangement within DAX-1 [PDF]
, 2002 DAX-1 [dosage-sensitive sex reversal, adrenal hypoplasia congenital (AHC) critical region on the X chromosome, gene 11 is a transcription factor expressed in the adrenal gland and at all levels of the gonadotrope axis.
Gaillard, R.C. +15 more
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Congenital hypogonadotropic hypogonadism due to GnRH receptor mutations in three brothers reveal sites affecting conformation and coupling [PDF]
, 2012 Congenital hypogonadotropic hypogonadism (CHH) is characterized by low gonadotropins and failure to progress normally through puberty. Mutations in the gene encoding the GnRH receptor (GNRHR1) result in CHH when present as compound heterozygous or ...
Newton, Claire +23 more
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Testosterone and aging male, a perspective from a developing country
The Aging Male, 2023 Purpose Hypogonadism is associated with a wide range of physical and psychological symptoms that can affect the overall health of men. However, in a developing country, there are several imposing challenges in the diagnosis and treatment of hypogonadism,
Bac Nguyen Hoai +4 more
doaj +1 more source
, 2017 In Poland, the number of men over the age of 50 years exceeds 6 million. It is estimated that about 2-6% of this population develops symptoms of late-onset hypogonadism (LOH). In men, testosterone deficiency increases slightly with age.
Wojciech Zgliczyński +2 more
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Unexpected difficult airway with hypogonadotropic hypogonadism [PDF]
, 2014 Ferda Yaman,1 Bengi Arslan,2 Ercan Yuvanç,3 Ünase Büyükkoçak1 1Anesthesiology and Reanimation Department, 2Otorhinolaryngology Head and Neck Surgery Department, 3Urology Department, Faculty of Medicine, Kirikkale University ...
Arslan B. +7 more
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Characteristics of a nationwide cohort of patients presenting with isolated hypogonadotropic hypogonadism (IHH) [PDF]
, 2018 Objective: Isolated hypogonadotropic hypogonadism (IHH) is a rare disorder with pubertal delay, normal (normoosmic-IHH, nIHH) or defective sense of smell (Kallmann syndrome, KS).
Krausz Csilla +30 more
core +4 more sources
A case report of a man with adult-onset idiopathic hypogonadotrophic hypogonadism [PDF]
, 2017 Background Adult-onset idiopathic hypogonadotrophic hypogonadism is a rare condition. It includes men who have no recognizable central nervous system abnormality nor other identifiable cause. They generally demonstrate age-appropriate puberty and normal
Davoren, Peter, Tang, Chee
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Prevalence and Risk Factors for Hypogonadism in Male Patients with Type 2 Diabetes Mellitus
Biomedical and Biotechnology Research Journal, 2023 Background: Type 2 diabetes mellitus (DM) can develop many complications, including hypogonadism, the prevalence of which is largely unknown. Male hypogonadism is an endocrine disease characterized by low-serum testosterone levels and is closely related ...
Srinidhi Rai +4 more
doaj +1 more source
Genetics of congenital central hypogonadism [PDF]
, 2022 The diagnostic suspicion of congenital central hypogonadism is based on clinical signs. Biochemical confirmation is challenging, especially after the postnatal activation stage of the hypothalamic–pituitary–testicular axis. Sertoli cell markers, like AMH
Grinspon, Romina
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Сахарный диабет, 2019 BACKGROUND: Male hypogonadism is a frequent complication of diabetes mellitus (DM) type 2; therefore, a study of its clinical and epidemiological characteristics is of interest.
Galina A. Mel'nichenko +2 more
doaj +1 more source