Results 101 to 110 of about 37,742 (258)

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

open access: yesAndrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell   +3 more
wiley   +1 more source

Nasal delivery of nerve growth factor rescue hypogonadism by up-regulating GnRH and testosterone in aging male miceResearch in context

open access: yesEBioMedicine, 2018
Background: Nerve growth factor (NGF) plays essential roles in regulating the development and maintenance of central sympathetic and sensory neurons. However, the effects of NGF on hypogonadism remain unexplored.
Jiao Luo   +11 more
doaj  

Spatial transcriptomics mapping of immune cell and TGFβ signalling pathway heterogeneity in testicular germ cell tumours

open access: yesAndrology, EarlyView.
Abstract Background Testicular germ cell tumours (TGCTs) are amongst the most common malignancies in young men, and their incidence is increasing worldwide. Tissue heterogeneity hampers efforts to understand how TGCT precursors (termed germ cell neoplasia in situ; GCNIS) emerge and progress, restricting elucidation of new strategies for diagnosis and ...
Sarah C. Moody   +6 more
wiley   +1 more source

The aporetic dialogs of Modena on gender differences: Is it all about testosterone? Episode III: Mathematics

open access: yesAndrology, EarlyView.
Abstract This report is the transcript of what was discussed in a convention at the Endocrinology Unit in Modena, Italy, in the form of the aporetic dialogs of ancient Greece. It is the third episode of a series of four discussions on the differences between males and females, with a multidisciplinary approach. In this work, the role of testosterone in
Giulia Brigante   +6 more
wiley   +1 more source

Emerging Trends in Patients Hospitalised With Cirrhosis—Aetiologies, Complications and Outcomes Compared to Other Chronic Health Conditions

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Rates of inpatient mortality and complication rates in cirrhosis remain high. With regard to inpatient outcomes, cirrhosis is falling behind other chronic health conditions. ABSTRACT Background The aetiologies, complications and overall burden of cirrhosis have undergone changes in recent years.
Julian Pohl   +9 more
wiley   +1 more source

Iron overload and morbidities in Chinese with non‐transfusion‐dependent thalassaemia

open access: yesBritish Journal of Haematology, EarlyView.
A cross‐sectional study in Hong Kong included 109 adult and paediatric Chinese patients with non‐transfusion dependent thalassaemia (NTDT). The study found significant chronic health issues in 52% of patients. More severe disease was observed in patients with non‐deletional α‐thalassaemia intermedia, β‐thalassaemia intermedia, advanced age and history ...
Wing‐yan Leung   +19 more
wiley   +1 more source

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