Treatment of congenital hypogonadotropic hypogonadism in male patients [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022 Congenital hypogonadotropic hypogonadism (CHH) is characterized by complete or partial failure of pubertal development because of inadequate secretion of gonadotropic hormones.
Hae Sang Lee +2 more
doaj +2 more sources
Genetics of hypogonadotropic hypogonadism [PDF]
Translational Andrology and Urology, 2021 Male congenital hypogonadotropic hypogonadism (CHH) is a heterogenous group of genetic disorders that cause impairment in the production or action of gonadotropin releasing hormone (GnRH). These defects result in dysfunction of the hypothalamic-pituitary-gonadal hormone axis, leading to low testosterone levels and impaired fertility.
Millar, Adam C. +2 more
openaire +3 more sources
Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay [PDF]
, 1999 Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Achermann, JC +12 more
core +3 more sources
Hypogonadotropic Hypogonadism Revisited
Clinics, 2013 Impaired testicular function, i.e., hypogonadism, can result from a primary testicular disorder (hypergonadotropic) or occur secondary to hypothalamic-pituitary dysfunction (hypogonadotropic).
Renato Fraietta +2 more
doaj +6 more sources
Unraveling Delayed Puberty: A Rare Case of Congenital Hypogonadotropic Hypogonadism Masked by Celiac Disease and Plummer–Vinson Syndrome [PDF]
Clinical Case ReportsCongenital hypogonadotropic hypogonadism (CHH) is a rare disorder that results in delayed puberty and infertility due to impaired secretion of gonadotropin‐releasing hormone (GnRH).
Osama Ahmad +7 more
doaj +2 more sources
HYPOGONADOTROPIC HYPOGONADISM (REVIEW)
Педиатрическая фармакология, 2008 The review is dedicated to the problem of hypogonadotropic hypogonadism. Modern ideas of the stages of normal sexual development of girls, etiology and pathogenesis of constitutional arrest of sexual development and hypogonadotropic hypogonadism are ...
E.V. Uvarova, E.V. Trifonova
doaj +3 more sources
Frequency of the allelic variant (Trp8Arg/Ile15Thr) of the luteinizing hormone gene in a Brazilian cohort of healthy subjects and in patients with hypogonadotropic hypogonadism [PDF]
Clinics, 2005 PURPOSE: To evaluate the frequency of allelic variant Trp8Arg/Ile15Thr in the luteinizing hormone beta-subunit gene in a Brazilian population of healthy subjects and in patients with hypogonadotropic hypogonadism.
Karina Berger +5 more
doaj +1 more source
Gestational Pituitary Apoplexy With Persistent Hypogonadotropic Hypogonadism [PDF]
AACE Endocrinol DiabetesMakhlouf J +5 more
europepmc +3 more sources
Male hypogonadotropic hypogonadism in various genetic disorders
Journal of Education, Health and Sport, 2020 Introduction and purpose: Male hypogonadism is diagnosed in patients with total testosterone under 9-12nmol/L (250-350ng/dl) in serum which is associated with numerous symptoms which can severely lower the quality of patients life.
Sylwiusz Niedobylski +6 more
doaj +1 more source
Pituitary imaging findings in pediatric patients with idiopathic hypogonadotropic hypogonadism
Endocrine Regulations, 2023 Objective. Idiopathic hypogonadotropic hypogonadism in children is a disease leading to a puberty absence. Some hypothalamic and pituitary defects cause hypogonadotropic hypogonadism.
Bitkin Eda Celebi +2 more
doaj +1 more source