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Hypoplastic Left Heart Syndrome [PDF]

open access: yes, 2020
Hypoplastic left heart syndrome (HLHS) is a type of congenital heart disease that results in the underdevelopment of the left-sided structures of the heart, including the mitral valve, left ventricle, aortic valve, ascending aorta, and aortic arch.
Cossu, Anne E., Kritzmire, Stacy M.
core   +4 more sources

Hypoplastic left heart syndrome [PDF]

open access: yesBMJ, 1997
Hypoplastic left heart syndrome is not an uncommon condition and accounts for about 10% of critical congenital heart disease in infants. Each year in Britain about 200 children will be born with this condition, which, unlike some other congenital cardiac lesions, usually occurs without serious associated non-cardiac malformations.
S W, O'Kelly, E L, Bove
  +7 more sources

Hypoplastic Left Heart Syndrome [PDF]

open access: yesRadioGraphics, 2001
Hypoplastic left heart syndrome (HLHS) is a complex combination of cardiac malformations that probably results from multiple developmental errors in the early stages of cardiogenesis and that, if left untreated, invariably proves fatal. A variety of chest radiographic findings are seen in patients with HLHS, including an enlarged cardiac silhouette ...
D M, Bardo   +4 more
openaire   +4 more sources

Transcriptome studies of congenital heart diseases: identifying current gaps and therapeutic frontiers

open access: yesFrontiers in Genetics, 2023
Congenital heart disease (CHD) are genetically complex and comprise a wide range of structural defects that often predispose to - early heart failure, a common cause of neonatal morbidity and mortality.
Nkechi Martina Odogwu   +6 more
doaj   +1 more source

Hypoplastic Left Heart Syndrome: A Case Report

open access: yesJournal of Nepal Medical Association, 2023
Hypoplastic left heart syndrome is a rare critical congenital heart defect constituting a prevalence of 1/3,500 to 1/12,500 live births in which there is obstructions to the blood flow within the left heart.
Sunil Raja Manandhar   +4 more
doaj   +1 more source

Use of Frogs as a Model to Study the Etiology of HLHS

open access: yesJournal of Cardiovascular Development and Disease, 2023
A frog is a classical model organism used to uncover processes and regulations of early vertebrate development, including heart development. Recently, we showed that a frog also represents a useful model to study a rare human congenital heart disease ...
Shuyi Nie
doaj   +1 more source

Hypoplastic Left Heart Syndrome: Is There a Role for Fetal Therapy?

open access: yesFrontiers in Pediatrics, 2022
During fetal life some cardiac defects may lead to diminished left heart growth and to the evolution of a form of hypoplastic left heart syndrome (HLHS).
Andreas Tulzer   +7 more
doaj   +1 more source

Hypoplastic left heart syndrome

open access: yesThe Annals of Thoracic Surgery, 1989
Hypoplastic left heart syndrome is a common lethal congenital cardiac malformation. The anatomy and physiology dictate therapy in the newborn period. Two stages of reconstructive surgical management are detailed.
J B, Smith, P, Vernon-Levett
openaire   +5 more sources

The Left Ventricular Myocardium in Hypoplastic Left Heart Syndrome

open access: yesJournal of Cardiovascular Development and Disease, 2022
Hypoplastic left heart syndrome (HLHS) is a collective term applied to severe congenital cardiac malformations, characterised by a combination of abnormalities mainly affecting the left ventricle, associated valves, and ascending aorta.
Bill Chaudhry   +6 more
doaj   +1 more source

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