Results 31 to 40 of about 43,375 (245)
Frontiers in Cell and Developmental Biology, 2020 Hypoplastic left heart syndrome (HLHS) is a clinically and anatomically severe form of congenital heart disease; however, its etiology remains largely unknown. We previously demonstrated that genetic variants in the MYH6 gene are significantly associated
Min‐su Kim +13 more
semanticscholar +1 more source
Fetal cardiac interventions: clinical and experimental research
Advances in Interventional Cardiology, 2016 Fetal cardiac interventions for congenital heart diseases may alleviate heart dysfunction, prevent them evolving into hypoplastic left heart syndrome, achieve biventricular outcome and improve fetal survival.
Shi-Min Yuan, Gulimila Humuruola
doaj +1 more source
Left-Sided Heart Defects and Laterality Disturbance in Hypoplastic Left Heart Syndrome
Journal of Cardiovascular Development and Disease, 2023 Hypoplastic left heart syndrome (HLHS) is a complex congenital heart disease characterized by hypoplasia of left-sided heart structures. The developmental basis for restriction of defects to the left side of the heart in HLHS remains unexplained.
Hisato Yagi, Cecilia W. Lo
doaj +1 more source
Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome
Circulation. Cardiovascular Quality and Outcomes, 2020 Background: Fetal aortic valvuloplasty (FAV) may prevent progression of midgestation aortic stenosis to hypoplastic left heart syndrome. However, FAV has well-established risks, and its survival benefit remains unknown.
Sarah S. Pickard +10 more
semanticscholar +1 more source
Cochlear Implantation in a Child With Hypoplastic Left-heart Syndrome: Clinical Case
Педиатрическая фармакология, 2019 Relevance. The hypoplastic left-heart syndrome at congenital heart disease has frequency of 261 cases out of 10,000 newborns. Children with hypoplastic left-heart syndrome can have comorbid congenital anomalies and acquired diseases that require ...
Margarita S. Kalugina +5 more
doaj +1 more source
Genetic Association between Hypoplastic Left Heart Syndrome and Cardiomyopathies.
Circulation Genomic and Precision Medicine, 2020 Background - Hypoplastic left heart syndrome (HLHS) with risk of poor outcome has been linked to MYH6 variants, implicating overlap in genetic etiologies of structural and myopathic heart disease.
Jeanne L. Theis +7 more
semanticscholar +1 more source
Fetal cardiac interventions: an update of therapeutic options
Brazilian Journal of Cardiovascular Surgery, 2014 Objective: This article aims to present updated therapeutic options for fetal congenital heart diseases. Methods: Data source for the present study was based on comprehensive literature retrieval on fetal cardiac interventions in terms of ...
Shi-Min Yuan
doaj +1 more source
The strong association of left-side heart anomalies with Kabuki syndrome [PDF]
Korean Journal of Pediatrics, 2015 PurposeKabuki syndrome is a multiple congenital malformation syndrome, with characteristic facial features, mental retardation, and skeletal and congenital heart anomalies.
Ja Kyoung Yoon +6 more
doaj +1 more source
Whole Genome Sequencing in Hypoplastic Left Heart Syndrome
Journal of Cardiovascular Development and Disease, 2022 Hypoplastic left heart syndrome (HLHS) is a genetically complex disorder. Whole genome sequencing enables comprehensive scrutiny of single nucleotide variants and small insertions/deletions, within both coding and regulatory regions of the genome ...
Jeanne L. Theis, Timothy M. Olson
doaj +1 more source
Health Expectations, 2020 To explore the role of antenatal counselling in how parents make treatment decisions following an antenatal diagnosis of Hypoplastic Left Heart Syndrome (HLHS).
S. Bertaud +4 more
semanticscholar +1 more source