Results 21 to 30 of about 1,601 (193)
Lupus anticoagulant hypoprothrombinemia syndrome - could it be a sequelae of COVID-19?
Blood Research, 2023 Nuša Matijašić +3 more
openalex +3 more sources
Clinical Case Reports, Volume 11, Issue 6, June 2023., 2023 Key Clinical Message Lupus anticoagulant caused aPTT prolongation in rare case can cause bleeding tendency especially when combined with other hemostasis abnormalities. In such cases, aPTT value can be corrected by immunosuppressants within several days of treatment.
Marlena Frydrysiak +3 more
wiley +1 more source
Case Reports in Rheumatology, Volume 2022, Issue 1, 2022., 2022 Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with unpredictable course and flares. The clinical manifestation can vary from mild to severe and life‐threatening disease. Infection is the primary cause of mortality in hospitalized SLE patients.
Mohamed M. Cheikh +7 more
wiley +1 more source
A case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene
Research and Practice in Thrombosis and Haemostasis, Volume 5, Issue 4, May 2021., 2021 Abstract Congenital prothrombin deficiency is an extremely rare, autosomal recessive bleeding disorder with a prevalence of 1 in 2 million individuals. Here, we report a case of congenital prothrombin deficiency with two concurrent mutations in the prothrombin gene (F2), affecting the heavy B chain.
Eman M. Mansory +5 more
wiley +1 more source
Monitoring of anticoagulation in thrombotic antiphospholipid syndrome
Journal of Thrombosis and Haemostasis, Volume 19, Issue 4, Page 892-908, April 2021., 2021 Abstract Anticoagulation is central to the management of thrombotic antiphospholipid syndrome (APS). The standard anticoagulant treatment for thrombotic APS is life‐long warfarin or an alternative vitamin K antagonist. The role of direct oral anticoagulants for thrombotic APS is not established due to the lack of definitive evidence and has recently ...
Hannah Cohen +2 more
wiley +1 more source
Hypoprothrombinemia: case report [PDF]
Blood, 1978 A patient with a significant history of spontaneous and posttraumatic bleeding was found to have hypoprothrombinemia. His prothrombin (factor II) activity by clotting assay was 9.5% and his factor II antigen was 5%. Crossed immunoelectrophoresis and sucrose density gradient ultracentrifugation of the patient's plasma showed his prothrombin to be ...
R R, Montgomery +2 more
openaire +3 more sources
Pathophysiology of coronavirus disease 2019 for wound care professionals
International Wound Journal, Volume 17, Issue 6, Page 1935-1940, December 2020., 2020 Abstract There is pressing urgency to understand the pathogenesis of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) which causes Coronavirus disease 2019 (COVID‐19). The tissue tropism of SARS‐CoV‐2 includes not only the lung but also the vascular and integumentary systems.
Sammy Al‐Benna
wiley +1 more source
Case Reports in Obstetrics and Gynecology, Volume 2020, Issue 1, 2020., 2020 We report a case of acquired factor XI deficiency with lupus anticoagulant (LA) in a 28‐year‐old primigravida who presented with finger pain and eruptions on her palms and fingers during the 3rd trimester of pregnancy. The patient complained of pain and reddening of the fingers at 30 weeks of gestation.
Rie Nakajima +6 more
wiley +1 more source
Hypoprothrombinemia Induced by Gossypol.
Experimental Biology and Medicine, 1951 SummaryGossypol induces hypoprothrombinemia in rabbits and pigs. Cottonseed meal containing free gossypol induces hypoprothrombinemia in young rabbits which begins after about 7 days feeding and passes through a maximum at approximately 17 days then slowly returns tto normal around 28 days. Gossypol is not as effective an anticoagulant as Dicumarol but
W S, HARMS, K T, HOLLEY
openaire +2 more sources