Androgen and estrogen receptor expression in the developing human penis and clitoris. [PDF]
To better understand how the human fetal penis and clitoris grows and remodels, we undertook an investigation to define active areas of cellular proliferation and programmed cell death spatially and temporally during development of human fetal external ...
Baskin, Laurence +6 more
core
Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case–Control Study in Newborn Boys [PDF]
Little is known on environmental risk factors for cryptorchidism and hypospadias, which are among the most frequent congenital abnormalities. The aim of our study was to identify risk factors for cryptorchidism and hypospadias, with a focus on potential ...
Alex Burdorf +8 more
core +2 more sources
Factors associated with reoperation in hypospadias surgery — A nationwide, population-based study
Background/Objective: To analyze the preoperative factors associated with the need for secondary surgery following primary urethroplasty. Methods: This study utilized a subset of the National Health Insurance Research Database, which includes the data on
Yu-Chuan Lu +6 more
doaj +1 more source
Defective spermatogenesis: Martin et al. respond [PDF]
This is an Open Access article - Copyright @ National Institute of Environmental Health Science.BACKGROUND: Male reproductive tract abnormalities such as hypospadias and cryptorchidism, and testicular cancer have been proposed to comprise a common ...
Boobis, Alan R. +5 more
core +2 more sources
Background Hypospadias is a congenital displacement of the urethral meatus in male newborns, being either an isolated defect at birth or a sign of sexual development disorders.
Magnani Cinzia +18 more
doaj +1 more source
Appraisal of hypospadias repair at University of Nigeria Teaching Hospital Enugu
Background: Hypospadias repair is one of the most common urologic surgeries performed in male children. Various surgical repairs and modifications of existing ones have evolved over the past decades.
Ijeoma Chioma Obianyo +2 more
doaj +1 more source
Novel associations in disorders of sex development: findings from the I-DSD registry [PDF]
Context: The focus of care in disorders of sex development (DSD) is often directed to issues related to sex and gender development. In addition, the molecular etiology remains unclear in the majority of cases.<p></p> Objective: To report ...
Ahmed +58 more
core +3 more sources
Contrasting mechanisms of penile urethral formation in mouse and human. [PDF]
This paper addresses the developmental mechanisms of formation of the mouse and human penile urethra and the possibility that two disparate mechanisms are at play.
Baskin, Laurence +5 more
core +2 more sources
PHENOTYPE-GENOTYPE AND PEDIGREE ANALYSIS OF ISOLATED HYPOSPADIAS PATIENTS
Objective: Hypospadias is a malformation in urethra which has many range of severity. A patient with Isolated hypospadias (IH), a mild disorder of sex development (DSD) has a hypospadias phenotype only. Hypospadias is considered as multifactorial disease
Nura Eky Vikawati +3 more
doaj +1 more source
Comparison of anogenital distance and correlation with vulvo-vaginal atrophy: a pilot study on premenopausal and postmenopausal women [PDF]
OBJECTIVES: Anogenital distance (AGD) represents the space between labia posterior commissure and anus. This was pilot study to investigate how menopause and so lack of oestrogens affects AGD. METHODS: A total of 109 patients were enrolled.
Benedetti Panici, Pierluigi +11 more
core +1 more source

