Results 181 to 190 of about 151,312 (311)

Bile Acids as Selective Gatekeepers of Dietary Lipid Absorption: Mechanistic Insights and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Their work provides evidence in murine models that the bile acid pool may function as a tunable filter whose selectivity for different fatty acids depends on bile acid concentration and composition. This framework suggests a selective decoupling of the absorption of excessive saturated fatty acids (SFAs) from that of beneficial polyunsaturated
Hao Wang, Yue Yang, Yulong Zhang, Yinling Li, Xuemei Ma, Haitao Wang   +5 more
wiley   +1 more source

Beyond mobility: A prospective study on diet and metabolism in hereditary spastic paraplegia. [PDF]

Metab Brain Dis
Erhardt C, Spatz IT, Herrmann HJ, Kohl Z, Zopf Y, Gassner H, Winkler J, Regensburger M.   +7 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS. [PDF]

BMC Med
Krishnamurthy SS, Buzatto AZ, Campkin C, Müller HP, Wiesner D, Weishaupt J, Klose V, Wiesenfarth M, Elmas Z, Herrmann C, Parlak Ö, Günther K, Saad R, Weiland U, Dupuis L, Ludolph A, Li L, Kassubek J, Dorst J, Roselli F.   +19 more
europepmc   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Food Insecurity was Associated With Poorer Sleep Quality and Increased Stress Among Dental Students at a HBCU and a Predominantly White School

Journal of Dental Education, EarlyView.
ABSTRACT Purpose The prevalence of food insecurity (FI) and its associated outcomes among undergraduate students have been widely researched, however studies focusing on FI among professional students are limited. This study investigated the associations between FI, sleep‐related variables, and stress among dental students from predominantly Black and ...
Brian Laurence, Teresa A. Marshall, Fang Qian, Gillian Robinson‐Warner, Archana Kumar, Nidhi Handoo, Cari Anderson   +6 more
wiley   +1 more source

Hypothalamic endoplasmic reticulum stress drives pubertal precocity due to early-onset obesity in female rodents. [PDF]

Proc Natl Acad Sci U S A
Rodríguez-Vázquez E, Aranda-Torrecillas Á, Jiménez-Puyer M, Freire-Agulleiro O, Sánchez-Tapia MJ, Ruiz-Cruz M, Heras V, López-Sancho M, Ongaro L, Perdices-López C, Bernard DJ, Pineda R, Gaytan F, López M, Castellano JM, Tena-Sempere M.   +15 more
europepmc   +1 more source

Automated competitive protein binding analysis and radioimmunoassay of serum cortisol without prior organic solvent extraction [PDF]

, 1974
Braun, J., Müller, O. A., Scriba, Peter Christian   +2 more
core   +1 more source

The impact of breast milk relaxin 2, oxytocin, and insulin‐like peptide 3 on neonatal growth parameters in early life

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives This study aims to quantify the levels of relaxin 2 (RLX2), oxytocin (OXT), and insulin‐like peptide 3 (INSL3) in colostrum (postpartum days 1–5, Visit 1) and mature breast milk (postpartum days 21–35, Visit 2), and to evaluate their associations with neonatal growth outcomes.
Hakan Doneray, Ayse Ozden, Guzide Tavlas, Halil Ibrahim Ozkan   +3 more
wiley   +1 more source

Possible Involvement of Hypothalamic Dysfunction in Long COVID Patients Characterized by Delayed Response to Gonadotropin-Releasing Hormone. [PDF]

Int J Mol Sci
Otsuka Y, Soejima Y, Nakano Y, Suyama A, Takase R, Oguni K, Masuda Y, Omura D, Sakurada Y, Matsuda Y, Hasegawa T, Honda H, Tokumasu K, Ueda K, Otsuka F.   +14 more
europepmc   +1 more source