Results 151 to 160 of about 245,222 (354)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Infertility and the Hypothalamus [Abridged] [PDF]

open access: bronze, 1966
A. C. Crooke, W. R. BUTT, P.V. Bertrand
openalex   +1 more source

Ictal asystole and ictal syncope must be differentiated from neurally mediated syncope

open access: yes
Epileptic Disorders, EarlyView.
Ryota Sasaki   +7 more
wiley   +1 more source

Puerariae lobatae Radix Alleviates Alcoholic Liver Injury by Regulating Circadian Rhythm and Intestinal Flora

open access: yesFood Frontiers, EarlyView.
(A) PLR contains a variety of isoflavones; (B) PLR attenuated alcoholic liver injury; (C) PLR improved intestinal flora dysbiosis; (D) PLR regulated circadian rhythm. ABSTRACT This study used Puerariae lobatae Radix (PLR) to explore its improvement mechanism in mice with alcoholic liver injury from the perspective of intestinal flora and transcriptome.
Yanfang Liao   +7 more
wiley   +1 more source

Oat Bran Supplementation Improves Glucose Metabolism, Food Addiction, and Gut Microbiota in Rats With High‐Fat Diet‐Induced Obesity

open access: yesFood Frontiers, EarlyView.
ABSTRACT Oat bran (OB), a byproduct of the oat milling process, is a nutrient‐dense cereal cultivated in cool, dry mountainous regions and is known for its potential health benefits. To explore its obesity‐alleviating effects and the underlying mechanisms, we examined the influence of OB on glucose metabolism, appetite‐regulating hormones, gut ...
Xue Bai   +6 more
wiley   +1 more source

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