Results 251 to 260 of about 318,025 (287)
Brain-Derived Neurotrophic Factor (BDNF) and Sex Differences in Metabolic Regulation. [PDF]
Zanesco AM, Velloso LA.
europepmc +1 more source
Microbiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation
Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...
Yue Tang +9 more
wiley +1 more source
Elucidating the neuromeric organization of the Mongolian gerbil brain. [PDF]
Lucero-Arteaga F +10 more
europepmc +1 more source
Spatial clustering is a critical step in spatially resolved transcriptomics. Here, we conducted a comprehensive benchmarking analysis of 14 spatial clustering methods using ~600 datasets, including both real‐world and simulated data spanning ten technologies and eight organs.
Renjie Chen +5 more
wiley +1 more source
Alteration of pituitary and hypothalamic membrane fluidity as a non-specific mode-of-action for reproductive effects with octamethylcyclotetrasiloxane. [PDF]
Meeks RG +4 more
europepmc +1 more source
ABSTRACT Neonicotinoids are widely used insecticides in agriculture, aquaculture, pet care, and urban pest control. Initially developed to selectively target the insect cholinergic system, their extensive use has raised concerns about adverse effects on nontarget vertebrates.
Kirthana Kunikullaya U +6 more
wiley +1 more source
Photoperiodic responsiveness in the DNA methylation and gene expression in the hypothalamus of ovariectomized and estradiol-treated ewes. [PDF]
He X +7 more
europepmc +1 more source
Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong +10 more
wiley +1 more source

