Results 31 to 40 of about 323,717 (308)
Hypothalamic Microinflammation: New Paradigm In Obesity And Metabolic Disease
Indonesian Biomedical Journal, 2020 BACKGROUND: Hypothalamus is the master regulator of body’s systemic homeostasis including energy balance, body temperature, sleep, blood pressure, and circadian rhythms.
Anna Meiliana +2 more
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionGestational diabetes (GDM) is associated with negative outcomes in mothers and their offspring, including greater risks of macrosomia at birth and the development of metabolic disorders.
Marina Galleazzo Martins +8 more
doaj +1 more source
It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]
, 2016 The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core +2 more sources
, 2013 A major function of the nervous system is to maintain the constancy of the internal environment. In 1878, Claude Bernard pointed out the remarkable distinction between our highly variable external environment (i.e., the environment that we live in and that is subject to major changes with regard to temperature, humidity, and food availability) and our ...
Sheina Orbell +113 more
+8 more sources
LogisticsThe ongoing issues in global supply chain disruptions have raised many concerns of port productivity, among which port congestion is a key issue.
Danilo Abril +2 more
doaj +1 more source
Distribution of choline acetyltransferase (ChAT) immunoreactivity in the brain of the teleost cyprinus carpio [PDF]
, 2018 Cholinergic systems play a role in basic cerebral functions and its dysfunction is associated with deficit in neurodegenerative disease. Mechanisms involved in human brain diseases, are often approached by using fish models, especially cyprinids, given ...
Casini, Arianna +3 more
core +2 more sources
A multi-disciplinary team model based on CBL in clinical teaching of hypothalamus-pituitary diseases [PDF]
Jichu yixue yu linchuang, 2020 Objective To explore the effect of case-based learning (CBL) combined with hypothalamus-pituitary MDT clinic in clinical teaching of hypothalamus pituitary diseases. Methods The trainees who participated in the hypothalamus-pituitary MDT discussion and
DUAN Lian, ZHENG Guang-yao, LU Lin, ZHU Hui-juan, YAO Yong, PAN Hui
doaj
Identification of sex hormone-binding globulin in the human hypothalamus [PDF]
, 2005 Gonadal steroids are known to influence hypothalamic functions through both genomic and non-genomic pathways. Sex hormone-binding globulin ( SHBG) may act by a non-genomic mechanism independent of classical steroid receptors.
Becchis M +35 more
core +1 more source
Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]
, 2016 We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M. +7 more
core +2 more sources
Molecular Brain, 2020 Leptin, secreted by peripheral adipocytes, binds the leptin receptor (Lepr) in the hypothalamus, thereby contributing to the regulation of satiety and body weight. Lepr is expressed in the embryonic brain as early as embryonic day 12.5.
Zhonggan Ren +7 more
doaj +1 more source