Results 31 to 40 of about 159,619 (232)

Endogenous circannual rhythm in LH secretion: insight from signal analysis coupled with mathematical modelling [PDF]

open access: yesPhilosophical Transactions of the Royal Society, Series A 367, 1908 (2009) 4759-4777, 2009
In sheep as in many vertebrates, the seasonal pattern of reproduction is timed by the annual photoperiodic cycle, characterized by seasonal changes in the daylength. The photoperiodic information is translated into a circadian profile of melatonin secretion. After multiple neuronal relays (within the hypothalamus), melatonin impacts GnRH (gonadotrophin
arxiv   +1 more source

Synchronization and entrainment of coupled circadian oscillators [PDF]

open access: yesInterface Focus 1, 167-176 (2011), 2010
Circadian rhythms in mammals are controlled by the neurons located in the suprachiasmatic nucleus of the hypothalamus. In physiological conditions, the system of neurons is very efficiently entrained by the 24-hour light-dark cycle. Most of the studies carried out so far emphasize the crucial role of the periodicity imposed by the light dark cycle in ...
arxiv   +1 more source

Hypothalamic expression analysis of m6A RNA methylation associated genes suggests a potential role of epitransciptomics in sexual maturation of Atlantic salmon [PDF]

open access: yesAquaculture, Volume 579, 30 January 2024, 740151
Better understanding the molecular processes contributing to variation in maturation timing is important for Atlantic salmon aquaculture, as early maturation causes considerable financial losses. The m6A RNA methylation is a conserved and dynamically reversible mechanism controlling gene expression in a myriad of biological processes.
arxiv   +1 more source

Observability of Hypergraphs [PDF]

open access: yesarXiv, 2023
In this paper we develop a framework to study observability for uniform hypergraphs. Hypergraphs, being extensions of graphs, allow edges to connect multiple nodes and unambiguously represent multi-way relationships which are ubiquitous in many real-world networks.
arxiv  

Assessment of the role of intracranial hypertension and stress on hippocampal cell apoptosis and hypothalamic-pituitary dysfunction after TBI

open access: yesScientific Reports, 2017
In recent years, hypopituitarism caused by traumatic brain injury (TBI) has been explored in many clinical studies; however, few studies have focused on intracranial hypertension and stress caused by TBI. In this study, an intracranial hypertension model,
Huajun Tan   +6 more
doaj   +1 more source

NAMPT and BMAL1 Are Independently Involved in the Palmitate-Mediated Induction of Neuroinflammation in Hypothalamic Neurons

open access: yesFrontiers in Endocrinology, 2020
Obesity is a prominent metabolic disease that predisposes individuals to multiple comorbidities, including type 2 diabetes mellitus, cardiovascular diseases, and cancer. Elevated circulating levels of fatty acids contribute to the development of obesity,
Andy Tran   +6 more
doaj   +1 more source

Microglia Don’t Treat All Neurons the Same: The Importance of Neuronal Subtype in Microglia-Neuron Interactions in the Developing Hypothalamus

open access: yesFrontiers in Cellular Neuroscience, 2022
Microglia are now well-known as integral regulators of brain development, phagocytosing whole neurons, and pruning weak or excess synapses in order to sculpt and refine immature circuits.
Zuri Ngozi, Jessica L. Bolton
doaj   +1 more source

Stability and Hopf bifurcation analysis of a four-dimensional hypothalamic-pituitary-adrenal axis model with distributed delays [PDF]

open access: yes, 2017
A four-dimensional mathematical model of the hypothalamus-pituitary-adrenal (HPA) axis is investigated, incorporating the influence of the GR concentration and general feedback functions. The inclusion of distributed time delays provides a more realistic modeling approach, since the whole past history of the variables is taken into account.
arxiv   +1 more source

Characterization of N6-Cyclohexyladenosine-Induced Hypothermia in Syrian Hamsters

open access: yesJournal of Pharmacological Sciences, 2005
The N6-cyclohexyladenosine (CHA)-induced hypothermia in Syrian hamsters was characterized as follows: intracerebroventricular injection of CHA-induced hypothermia and the potency was increased by lowering the ambient temperature.
Mitsuteru Shintani   +3 more
doaj  

Investigating the relationship between hippocampus/dentate gyrus volume and hypothalamus metabolism in participants with major depressive disorder

open access: yesScientific Reports
Reduced hippocampal volume occurs in major depressive disorder (MDD), potentially due to elevated glucocorticoids from an overactivated hypothalamus–pituitary–adrenal (HPA) axis.
Karen Lin   +5 more
doaj   +1 more source

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