Results 31 to 40 of about 245,222 (354)
Molecular Brain, 2020 Leptin, secreted by peripheral adipocytes, binds the leptin receptor (Lepr) in the hypothalamus, thereby contributing to the regulation of satiety and body weight. Lepr is expressed in the embryonic brain as early as embryonic day 12.5.
Zhonggan Ren +7 more
doaj +1 more source
The Paraventricular Nucleus of the Hypothalamus: Development, Function, and Human Diseases.
Endocrinology, 2018 The paraventricular nucleus of the hypothalamus (PVH), located in the ventral diencephalon adjacent to the third ventricle, is a highly conserved brain region present in species from zebrafish to humans. The PVH is composed of three main types of neurons,
Cheng Qin, Jiaheng Li, K. Tang
semanticscholar +1 more source
A multi-disciplinary team model based on CBL in clinical teaching of hypothalamus-pituitary diseases [PDF]
Jichu yixue yu linchuang, 2020 Objective To explore the effect of case-based learning (CBL) combined with hypothalamus-pituitary MDT clinic in clinical teaching of hypothalamus pituitary diseases. Methods The trainees who participated in the hypothalamus-pituitary MDT discussion and
DUAN Lian, ZHENG Guang-yao, LU Lin, ZHU Hui-juan, YAO Yong, PAN Hui
doaj
The Pan African Medical Journal, 2021 Adipsia is a rare condition characterized by a lack of thirst due to a defect in specific osmoreceptors located in the hypothalamus. The disorder is characterized by failure to maintain the body’s normal plasma osmolality (POSM), resulting in chronic or ...
Mohammed Abdulrahman Alhassan +3 more
doaj +1 more source
Microarray profiling of hypothalamic gene expression changes in Huntington’s disease mouse models
Frontiers in Neuroscience, 2022 Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington’s disease (HD), a neurodegenerative disorder caused by an expanded cytosine-adenine-guanine (CAG) repeat in the ...
Elna Dickson +6 more
doaj +1 more source
MicroRNAs in the Hypothalamus [PDF]
Neuroendocrinology, 2013 MicroRNAs (miRNAs) are short (∼22 nucleotides) non-coding ribonucleic acid (RNA) molecules that negatively regulate the expression of protein-coding genes. Posttranscriptional silencing of target genes by miRNA is initiated by binding to the 3′-untranslated regions of target mRNAs, resulting in specific cleavage and subsequent degradation of the mRNA ...
Meister, Björn +2 more
openaire +3 more sources
European Journal of Histochemistry, 2022 Glyphosate, aminomethylphosphonic acid (AMPA), and glyphosate-based herbicides altered the neuroendocrine axis, the content of brain neurotransmitters, and behavior in experimental animal models.
Ewing Duque-Díaz +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
Treatment with Synthetic Glucocorticoids and the Hypothalamus-Pituitary-Adrenal Axis
International Journal of Molecular Sciences, 2017 Chronic glucocorticoid (GC) treatment represents a widely-prescribed therapy for several diseases in consideration of both anti-inflammatory and immunosuppressive activity but, if used at high doses for prolonged periods, it can determine the systemic ...
R. Paragliola +3 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source