Successful fibrinolytic and therapeutic hypothermic management of cardiac arrest following massive pulmonary embolism [PDF]
Clinical and Experimental Emergency Medicine, 2015 Massive pulmonary embolism (MPE) with hemodynamic instability is a clinical condition with a poor prognosis and high mortality rates. There are no definitive treatment options for cardiac arrest due to MPE. A 52-year-old female presented at our emergency
Eunsil Ko +10 more
doaj +1 more source
Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.
New England Journal of Medicine, 2002 BACKGROUND Cardiac arrest outside the hospital is common and has a poor outcome. Studies in laboratory animals suggest that hypothermia induced shortly after the restoration of spontaneous circulation may improve neurologic outcome, but there have been ...
Stephen A Bernard +6 more
semanticscholar +1 more source
Targeted temperature management for postcardiac arrest syndrome [PDF]
Journal of Neurocritical Care, 2020 Neurocritical care management to improve neurologic outcome for postcardiac arrest syndrome (PCAS) has focused considerably on targeted temperature management (TTM). TTM attenuates the destructive processes following ischemia/reperfusion in PCAS.
Yasuhiro Kuroda, Kenya Kawakita
doaj +1 more source
PLoS Genetics, 2017 Mutations in the neuron-specific α3 isoform of the Na+/K+-ATPase are found in patients suffering from Rapid onset Dystonia Parkinsonism and Alternating Hemiplegia of Childhood, two closely related movement disorders.
T. Isaksen +7 more
semanticscholar +1 more source
Mild hypothermia in the prevention of brain edema in acute liver failure: mechanisms and clinical prospects [PDF]
, 2002 Mild hypothermia (32 degrees C-35 degrees C) reduces intracranial pressure in patients with acute liver failure and may offer an effective adjunct therapy in the management of these patients.
Butterworth, Roger +2 more
core +1 more source
Subnormothermic Perfusion in the Isolated Rat Liver Preserves the Antioxidant Glutathione and Enhances the Function of the Ubiquitin Proteasome System. [PDF]
, 2016 The reduction of oxidative stress is suggested to be one of the main mechanisms to explain the benefits of subnormothermic perfusion against ischemic liver damage. In this study we investigated the early cellular mechanisms induced in isolated rat livers
Alva, Norma +4 more
core +4 more sources
Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes [PDF]
, 2019 Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia ...
Berger, Felix +6 more
core +1 more source
Acute Physiologic and Chronic Health Examination II and Sequential Organ Failure Assessment Scores for Predicting Outcomes of Out-of-Hospital Cardiac Arrest Patients Treated with Therapeutic Hypothermia [PDF]
Korean Journal of Critical Care Medicine, 2014 BACKGROUND: The aim of this study was to assess the relationship between acute physiologic and chronic health examination (APACHE) II and sequential organ failure assessment (SOFA) scores and outcomes of post-cardiac arrest patients treated with ...
Sung Joon Kim +5 more
doaj +1 more source
Therapeutic hypothermia and neurological outcome after cardiac arrest [PDF]
Vojnosanitetski Pregled, 2011 Introduction/Aim. The most important clinically relevant cause of global cerebral ischemia is cardiac arrest. Clinical studies showed a marked neuroprotective effect of mild hypothermia in resuscitation.
Petrović Milovan +6 more
doaj +1 more source
Brief Rewarming Blunts Hypothermia-Induced Alterations in Sensation, Motor Drive and Cognition
Frontiers in Physiology, 2016 Background: It is well known that cold exposure experienced during occupational or recreational activities may adversely affect motor, cognitive performance, and health.
M. Brazaitis +5 more
semanticscholar +1 more source