Dexmedetomidine Use in Patients with 33℃ Targeted Temperature Management: Focus on Bradycardia as an Adverse Effect [PDF]
Background This study aimed to investigate bradycardia as an adverse effect after administration of dexmedetomidine during 33℃ target temperature management.
Hyo-yeon Seo+4 more
doaj +1 more source
Targeted temperature management for postcardiac arrest syndrome [PDF]
Neurocritical care management to improve neurologic outcome for postcardiac arrest syndrome (PCAS) has focused considerably on targeted temperature management (TTM). TTM attenuates the destructive processes following ischemia/reperfusion in PCAS.
Yasuhiro Kuroda, Kenya Kawakita
doaj +1 more source
Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling [PDF]
Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Albrecht, Martin+9 more
core +3 more sources
Hypoxia elicits hyperventilation and hypothermia, but the mechanisms involved are not well understood. The nitric oxide (NO) pathway is involved in hypoxia-induced hypothermia and hyperventilation, and works as a neuromodulator in the central nervous ...
G. Fabris+2 more
doaj +1 more source
Hemoglobin concentration is associated with neurologic outcome after cardiac arrest in patients treated with targeted temperature management [PDF]
Objective The objective of this study was to test the hypothesis that hemoglobin concentration after return of spontaneous circulation (ROSC) is associated with neurologic outcome after cardiac arrest in patients treated with targeted temperature ...
Daesung Kim+5 more
doaj +1 more source
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono+8 more
wiley +1 more source
Use of an external-cooling device for the treatment of heat stroke [PDF]
Heat stroke is caused by losing control of one’s body temperature. It can be life threatening without proper treatment. In this case report, we describe a heat stroke patient treated with an external-cooling device, which is commonly used for therapeutic
Byung-Chan Lee+3 more
doaj +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin+7 more
wiley +1 more source
Effects of therapeutic hypothermia on white matter injury from murine neonatal hypoxia-ischemia. [PDF]
BackgroundTherapeutic hypothermia (TH) is the standard of care for neonates with hypoxic-ischemic encephalopathy, but it is not fully protective in the clinical setting.
Ferriero, Donna M+4 more
core +2 more sources
Limited Therapeutic Time Windows of Mild-to-Moderate Hypothermia in a Focal Ischemia Model in Rat
Although many studies have shown the great potential of induced hypothermia in stroke treatment, we recognize that there are limitations to the protective effects of hypothermia even in the laboratory.
Heng Zhao, Gary Steinberg
doaj +1 more source