Results 11 to 20 of about 43,432 (280)

Pharmacodynamic properties for inhibition of cAMP- and cGMP elimination by pentoxifylline remain unaltered in vitro during hypothermia [PDF]

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2022
Background Rewarming from hypothermia is associated with severe complications, one of which is hypothermia-induced cardiac dysfunction. This condition is characterized by decreased cardiac output accompanied by increased total peripheral resistance. This
Anders Lund Selli, Adrina Kalasho Kuzmiszyn, Natalia Smaglyukova, Timofey Kondratiev, Ole-Martin Fuskevåg, Georg Sager, Erik Sveberg Dietrichs   +6 more
doaj   +2 more sources

The Protective Role and Mechanism of Mild Therapeutic Hypothermia Protection on Brain Cells

Neuropsychiatric Disease and Treatment, 2023
Suixin Liang,1 Yunxing Ti,2 Xiuhong Li,1 Wenjia Zhou1 1Department of CICU, Shenzhen Children’s Hospital, Shenzhen City, Guangdong Province, People’s Republic of China; 2Department of Cardiothoracic Surgery, Shenzhen Children’s Hospital, Shenzhen City ...
Liang S, Ti Y, Li X, Zhou W
doaj   +1 more source

Maintaining intravenous volume mitigates hypothermia-induced myocardial dysfunction and accumulation of intracellular Ca2+ [PDF]

, 2021
Previous research exploring pathophysiological mechanisms underlying circulatory collapse after rewarming victims of severe accidental hypothermia has documented post-hypothermic cardiac dysfunction and hypothermia-induced elevation of intracellular Ca2+
Tveita, Torkjel, Schanche, Torstein, Jan Harald Nilsen, Torstein Schanche, Timofei V. Kondratiev, Nilsen, Jan Harald, Hevrøy, Olav, Sieck, Gary C., Olav Hevrøy, Torkjel Tveita, Kondratiev, Timofei V., Gary C. Sieck   +11 more
core   +1 more source

Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation [PDF]

, 2010
Introduction: Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion in-jury.
Meybohm, Patrick, Zitta, Karina, Grünewald, Matthias Lars, Albrecht, Martin, Zacharowski, Kai, Lucius, Ralph, Hensler, Johannes, Bein, Berthold, Fösel, Nikola   +8 more
core   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Induced and Accidental Hypothermia

Critical Care and Resuscitation, 2000
To review human thermoregulation and the pathophysiology and management of induced and accidental hypothermia.A review of studies reported over ten years from 1990 to 2000 and identified through a MEDLINE search of the English-language literature on thermoregulation and induced and accidental hypothermia.Hypothermia is defined as a core temperature ...
E, Connolly, L I, Worthley
openaire   +2 more sources

European society of intensive care medicine study of therapeutic hypothermia (32-35 °C) for intracranial pressure reduction after traumatic brain injury (the Eurotherm3235Trial). [PDF]

, 2011
BACKGROUND: Traumatic brain injury is a major cause of death and severe disability worldwide with 1,000,000 hospital admissions per annum throughout the European Union.Therapeutic hypothermia to reduce intracranial hypertension may improve patient ...
Mascia, L, Polderman, Kees, Andrews, Peter JD, Harris Bridget A, P. J. Andrews, Harris, Bridget A, Mascia L, Andrews, Peter J. D., Battison CG, Battison, CG, Harris, Bridget, B. A. Harris, Murray Gordon D, G. D. Murray, Sinclair HL, Sinclair, Helen Louise, Murray GD, De Backer D, Battison, Claire G., the Eurotherm3235Trial collaborators, Stocchetti, N, Eurotherm 3235 trials collaborators, Menon, David K, Sinclair, HL, D. K. Menon, H. Shakur, Sinclair, Helen L.Helen, G. Citerio, Citerio, Giuseppe, Shakur, H, Polderman, Kees H., De Backer, Daniel, Andrews, Peter, the Eurotherm3235Trial collaborators., Citerio G, Stocchetti Nino, C. G. Battison, Eurotherm3235Trial collaborators, Polderman Kees H, Citerio Giuseppe, De Backer Daniel, Shakur H, Andrews, PJD, Harris, BA, Menon, David Krishna, Mascia, Luciana, Mascia Luciana, K. H. Polderman, Citerio, G, Shakur, Haleema, N. Stocchetti, Stocchetti N, Battison Claire G, H. L. Sinclair, Harris BA, Menon DK, Shakur Haleema, L. K. Mascia, Battison, Claire, Harris, Bridget A., Murray, Gordon, Polderman KH, Andrews Peter JD, Murray, Gordon D, De Backer, D, Andrews PJ, Menon David K, Stocchetti, Nino, Murray, Gordon D., Menon, DK, Sinclair Helen, Battison, Claire G, Menon, David K., D. De Backer, Polderman, Kees H, Murray, GD, Polderman, KH   +76 more
core   +1 more source

Targeted temperature management for postcardiac arrest syndrome [PDF]

Journal of Neurocritical Care, 2020
Neurocritical care management to improve neurologic outcome for postcardiac arrest syndrome (PCAS) has focused considerably on targeted temperature management (TTM). TTM attenuates the destructive processes following ischemia/reperfusion in PCAS.
Yasuhiro Kuroda, Kenya Kawakita
doaj   +1 more source

Hypothermia in Trauma [PDF]

, 2021
Hypothermia in trauma patients is a common condition. It is aggravated by traumatic hemorrhage, which leads to hypovolemic shock. This hypovolemic shock results in a lethal triad of hypothermia, coagulopathy, and acidosis, leading to ongoing bleeding ...
van Veelen, Michiel J., Michiel J. van Veelen, Monika Brodmann Maeder, Brodmann Maeder, Monika   +3 more
core   +1 more source