Therapeutic hypothermia and neurological outcome after cardiac arrest [PDF]
Introduction/Aim. The most important clinically relevant cause of global cerebral ischemia is cardiac arrest. Clinical studies showed a marked neuroprotective effect of mild hypothermia in resuscitation.
Petrović Milovan +6 more
doaj +1 more source
Cortical organotypic slice cultures as a tool to analyze the neurovascular unit in hypoxia/ischemia and hypothermia-induced neuroprotection [PDF]
Neurons and glial cells of the central nervous system (CNS) communicate and work together to function and execute an array of complex tasks. In addition to them a third cell type which also works to keep the brain alive are the cerebral endothelial cells
Chip, Sophorn
core +1 more source
Randomized preclinical study of machine perfusion in vascularized composite allografts
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin +7 more
wiley +1 more source
Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model
Background. The deterioration of hemodynamics instantly endangers the patients’ life after polytrauma. As accidental hypothermia frequently occurs in polytrauma, therapeutic hypothermia still displays an ambivalent role as the impact on the ...
Matthias Weuster +10 more
doaj +1 more source
Acute Physiologic and Chronic Health Examination II and Sequential Organ Failure Assessment Scores for Predicting Outcomes of Out-of-Hospital Cardiac Arrest Patients Treated with Therapeutic Hypothermia [PDF]
BACKGROUND: The aim of this study was to assess the relationship between acute physiologic and chronic health examination (APACHE) II and sequential organ failure assessment (SOFA) scores and outcomes of post-cardiac arrest patients treated with ...
Sung Joon Kim +5 more
doaj +1 more source
Therapeutic hypothermia for severe adult Herpes simplex virus encephalitis [PDF]
Despite antiviral treatment and advances in critical care, the Herpes simplex encephalitis (HSE) still has a poor outcome in a significant portion of patients.
Baršić, Bruno, Kutleša, Marko
core +1 more source
Targeted temperature management in neurointensive care
The clinical prognosis of acute severe brain injury is poor, and therapeutic hypothermia in targeted temperature management (TTM) is considered to be one of the most effective neuroprotective methods, which might effectively improve the prognosis of ...
QU Xin, ZHAO Hao, SHANG Feng, WANG Ning
doaj +1 more source
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono +8 more
wiley +1 more source
Limited Therapeutic Time Windows of Mild-to-Moderate Hypothermia in a Focal Ischemia Model in Rat
Although many studies have shown the great potential of induced hypothermia in stroke treatment, we recognize that there are limitations to the protective effects of hypothermia even in the laboratory.
Heng Zhao, Gary Steinberg
doaj +1 more source
Characterization of N6-Cyclohexyladenosine-Induced Hypothermia in Syrian Hamsters
The N6-cyclohexyladenosine (CHA)-induced hypothermia in Syrian hamsters was characterized as follows: intracerebroventricular injection of CHA-induced hypothermia and the potency was increased by lowering the ambient temperature.
Mitsuteru Shintani +3 more
doaj +1 more source

