Results 31 to 40 of about 74,844 (266)

Hypothermia Reduces Mortality, Prevents the Calcium Plateau, and Is Neuroprotective Following Status Epilepticus in Rats

open access: yesFrontiers in Neurology, 2018
Status Epilepticus (SE) is a major neurological emergency and is considered a leading cause of Acquired Epilepsy (AE). We have shown that SE produces neuronal injury and prolonged alterations in hippocampal calcium levels ([Ca2+]i) that may underlie the ...
Kristin F. Phillips   +4 more
doaj   +1 more source

Targeted temperature management in neurointensive care

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2023
The clinical prognosis of acute severe brain injury is poor, and therapeutic hypothermia in targeted temperature management (TTM) is considered to be one of the most effective neuroprotective methods, which might effectively improve the prognosis of ...
QU Xin, ZHAO Hao, SHANG Feng, WANG Ning
doaj   +1 more source

Mild hypothermia does not attenuate platelet aggregation and may even increase ADP-stimulated platelet aggregation after clopidogrel treatment

open access: yesThrombosis Journal, 2009
Background Mild hypothermia is currently standard of care for cardiac arrest patients in many hospitals and a common belief is that hypothermia attenuates platelet aggregation.
Erlinge David   +2 more
doaj   +1 more source

Cold at the Core: Osborn Waves in Neurosarcoidosis-Induced Central Hypothermia

open access: yesCase Reports in Cardiology, 2019
Osborn waves, or J waves, initially described by John Osborn in 1953 in hypothermic dog experiments, are highly sensitive and specific for hypothermia. Initially thought to be secondary to a hypothermia-induced “injury current,” they have more recently ...
Gregory Scott Troutman   +3 more
doaj   +1 more source

Influence of cold on host-parasite interactions. [PDF]

open access: yes, 1963
pt.
Arctic Aeromedical Laboratory (U.S.)   +2 more
core   +2 more sources

Mild hypothermia alleviates brain oedema and blood-brain barrier disruption by attenuating tight junction and adherens junction breakdown in a swine model of cardiopulmonary resuscitation.

open access: yesPLoS ONE, 2017
Mild hypothermia improves survival and neurological recovery after cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). However, the mechanism underlying this phenomenon is not fully elucidated. The aim of this study was to determine whether mild
Jiebin Li   +6 more
doaj   +1 more source

Outcome and current status of therapeutic hypothermia after out-of-hospital cardiac arrest in Korea using data from the Korea Hypothermia Network registry [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2014
ObjectiveTherapeutic hypothermia (TH) has become the standard strategy for reducing brain damage in the postresuscitation period. The aim of this study was to investigate current TH performance and outcomes in out-of-hospital cardiac arrest (OHCA ...
Byung Kook Lee   +24 more
doaj   +1 more source

Induced and Accidental Hypothermia

open access: yesCritical Care and Resuscitation, 2000
To review human thermoregulation and the pathophysiology and management of induced and accidental hypothermia.A review of studies reported over ten years from 1990 to 2000 and identified through a MEDLINE search of the English-language literature on thermoregulation and induced and accidental hypothermia.Hypothermia is defined as a core temperature ...
E, Connolly, L I, Worthley
openaire   +2 more sources

Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]

open access: yes, 2001
Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de,   +5 more
core   +1 more source

Effect of Trans-Nasal Evaporative Intra-arrest Cooling on Functional Neurologic Outcome in Out-of-Hospital Cardiac Arrest : The PRINCESS Randomized Clinical Trial [PDF]

open access: yes, 2019
© 2019 American Medical Association. All rights reserved.Importance: Therapeutic hypothermia may increase survival with good neurologic outcome after cardiac arrest.
Abella   +43 more
core   +3 more sources

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