Results 41 to 50 of about 43,432 (280)

Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling

open access: yes, 2009
Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Meybohm, Patrick   +19 more
core   +1 more source

A case report of acute hypothermia during initial inpatient clozapine titration with review of current literature on clozapine-induced temperature dysregulations

open access: yesBMC Psychiatry, 2020
Background Here we describe a unique case of clozapine-associated hypothermia during initial titration of this medication in an acute inpatient psychiatry setting. Only a handful of cases on this topic have been published.
Bradley G. Burk   +2 more
doaj   +1 more source

The RNA-binding protein RBM3 is involved in hypothermia induced neuroprotection

open access: yesNeurobiology of Disease, 2011
Induced hypothermia is the only therapy with proven efficacy to reduce brain damage after perinatal asphyxia. While hypothermia down-regulates global protein synthesis and cell metabolism, low temperature induces a small subset of proteins that includes ...
Sophorn Chip   +6 more
doaj   +1 more source

Idioventricular Rhythm Induced by Therapeutic Hypothermia

open access: yes, 2011
We report the case of a 11 -year-old girl with fulminant myocarditis and cardiogenic shock who received cardiopulmonary resuscitation and extracorporeal membrane oxygenation support.
吳恩婷;黃書健;紀乃新;林銘泰;柯文哲;王水深;王主科;吳美環   +1 more
core   +1 more source

Neuroprotection by Therapeutic Hypothermia

open access: yesFrontiers in Neuroscience, 2019
Hypothermia therapy is an old and important method of neuroprotection. Until now, many neurological diseases such as stroke, traumatic brain injury, intracranial pressure elevation, subarachnoid hemorrhage, spinal cord injury, hepatic encephalopathy, and
Ying-Jian Sun   +3 more
doaj   +1 more source

Comparison between Gel Pad Cooling Device and Water Blanket during Target Temperature Management in Cardiac Arrest Patients [PDF]

open access: yesAcute and Critical Care, 2018
Background: Target temperature management (TTM) improves neurological outcomes for comatose survivors of out-of-hospital cardiac arrest. We compared the efficacy and safety of a gel pad cooling device (GP) and a water blanket (WB) during TTM. Methods: We
Yoon Sun Jung   +3 more
doaj   +1 more source

Bioorthogonal Photoactivation of 2‐Nitrobenzyl Caged Doxorubicin Anticancer Prodrugs on Gold Nanostars

open access: yesAdvanced Materials, EarlyView.
Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno   +15 more
wiley   +1 more source

Facts and Fiction: The Impact of Hypothermia on Molecular Mechanisms following Major Challenge

open access: yesMediators of Inflammation, 2012
Numerous multiple trauma and surgical patients suffer from accidental hypothermia. While induced hypothermia is commonly used in elective cardiac surgery due to its protective effects, accidental hypothermia is associated with increased posttraumatic ...
Michael Frink   +4 more
doaj   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

open access: yesAdvanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu   +17 more
wiley   +1 more source

Effect of hypothermia on haemostasis and bleeding risk: a narrative review

open access: yesJournal of International Medical Research, 2019
It must be remembered that clinically important haemostasis occurs in vivo and not in a tube, and that variables such as the number of bleeding events and bleeding volume are more robust measures of bleeding risk than the results of analyses.
Thomas Kander, Ulf Schött
doaj   +1 more source

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