Results 61 to 70 of about 6,581,632 (222)

The effect of hypothermia therapy on cortical laminar disruption following ischemic injury in neonatal mice. [PDF]

open access: yesPLoS ONE, 2013
Hypothermia has been proposed as a treatment for reducing neuronal damage in the brain induced by hypoxic ischemia. In the developing brain, hypoxic ischemia-induced injury may give rise to cerebral palsy (CP).
Hiroyuki Kida   +5 more
doaj   +1 more source

Altering temperature in a mammalian body [PDF]

open access: yes, 2013
The present application relates to systems and methods for altering temperature in a mammalian body. Optionally, the systems and methods can be used to lower or raise core body temperature of a mammalian subject.
Diller, Kenneth R.   +2 more
core   +1 more source

Cold Shock Induced Protein RBM3 but Not Mild Hypothermia Protects Human SH-SY5Y Neuroblastoma Cells From MPP+-Induced Neurotoxicity

open access: yesFrontiers in Neuroscience, 2018
The cold shock protein RBM3 can mediate mild hypothermia-related protection in neurodegeneration such as Alzheimer's disease. However, it remains unclear whether RBM3 and mild hypothermia provide same protection in model of Parkinson's disease (PD), the ...
Hai-Jie Yang   +8 more
doaj   +1 more source

Pharmacodynamic properties for inhibition of cAMP- and cGMP elimination by pentoxifylline remain unaltered in vitro during hypothermia

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2022
Background Rewarming from hypothermia is associated with severe complications, one of which is hypothermia-induced cardiac dysfunction. This condition is characterized by decreased cardiac output accompanied by increased total peripheral resistance. This
Anders Lund Selli   +6 more
doaj   +1 more source

Osborn Waves: History and Significance [PDF]

open access: yes, 2004
The Osborn wave is a deflection with a dome or hump configuration occurring at the R-ST junction (J point) on the ECG (Fig. 1). In the historical view, different names have been used for this wave in the medical literature, such as “camel-hump sign ...
Atarashi, Hirotsugu   +6 more
core   +2 more sources

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1 [PDF]

open access: yes, 2015
TNF is a central actor during inflammation and a well-recognized drug target for inflammatory diseases. We found that the mouse strain SPRET/Ei, known for extreme and dominant resistance against TNF-induced shock, displays weak expression of TNF receptor
Dejager, Lien   +11 more
core   +1 more source

Preclinical discovery of duloxetine for the treatment of depression [PDF]

open access: yes, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María   +4 more
core   +2 more sources

Use of an external-cooling device for the treatment of heat stroke [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2014
Heat stroke is caused by losing control of one’s body temperature. It can be life threatening without proper treatment. In this case report, we describe a heat stroke patient treated with an external-cooling device, which is commonly used for therapeutic
Byung-Chan Lee   +3 more
doaj   +1 more source

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]

open access: yes, 2014
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M   +5 more
core   +2 more sources

Limb Hypothermia for Preventing Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer Patients: A Pilot Study

open access: yesFrontiers in Oncology, 2017
Background Peripheral neuropathy (PN) due to paclitaxel is a common dose-limiting toxicity with no effective prevention or treatment. We hypothesize that continuous-flow limb hypothermia can reduce paclitaxel-induced PN.
R. Sundar   +17 more
semanticscholar   +1 more source

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