Results 11 to 20 of about 1,877,793 (121)

Clinical assessment of Renal Ischaemic Injury and the Role of Cryopreservation; Peritoneal Cooling an Non-Heart-Beating Donation and Topical Cooling for Laparoscopic Surgery [PDF]

The project aims focussed on three main areas of study; ischaemic injury assessment, laparoscopic renal cryopreservation and peritoneal cooling for non-heart-beating organ donation.
Navarro, Alex
core   +6 more sources

Hypothermic, oxygenated perfusion (HOPE) provides cardioprotection via succinate oxidation prior to normothermic perfusion in a rat model of donation after circulatory death (DCD) [PDF]

, 2021
In donation after circulatory death (DCD), cardiac grafts are subjected to warm ischemia in situ, prior to a brief period of cold, static storage (CSS) at procurement, and ex situ, normothermic, machine perfusion (NMP) for transport and graft evaluation.
Arnold, Maria, Wyss, Rahel K., Segiser, Adrian, Carrel, Thierry P, Carrel, Thierry P., Mueller, Matteo, Longnus, Sarah L; https://orcid.org/, Dutkowski, Philipp, Wyss, Rahel K, Longnus, Sarah L., Méndez Carmona, Natalia   +10 more
core   +1 more source

Viability Criteria during Liver Ex-Situ Normothermic and Hypothermic Perfusion [PDF]

, 2022
With the increased use of extended-criteria donors, machine perfusion became a beneficial alternative to cold storage in preservation strategy for donor livers with the intent to expand donor pool. Both normothermic and hypothermic approach achieved good
Riccardo De Carlis, De Carlis, Riccardo, Torri, Francesco, Melandro, Fabio, De Simone, Paolo, De Carlis, Luciano, Andrea Lauterio, Davide Ghinolfi, Ghinolfi, Davide, Francesco Torri, Paolo De Simone, Fabio Melandro, Lauterio, Andrea, Luciano De Carlis   +13 more
core   +1 more source

Evaluation of target temperature on effectiveness of myocardial preservation during hypothermic machine perfusion. [PDF]

JHLT Open
Background: Ex-situ heart perfusion (ESHP) has been proposed as an optimal method for preserving donated hearts prior to transplantation. Hypothermic oxygenated perfusion (HOP) is a simple method from a device design perspective, with enhanced safety ...
da Silva GMA, Wagner MJ, Hatami S, Hassanzadeh P, Wang X, Adam BA, Nagendran J, Freed DH.   +7 more
europepmc   +2 more sources

Hypothermic liver perfusion [PDF]

, 2017
PURPOSE OF REVIEW: The review describes recent developments in hypothermic machine liver perfusion with a special focus on underlying protective mechanisms, and the role of this perfusion technique in high-risk donor-recipient combinations.
Philipp Dutkowski, Schlegel, Andrea, Xavier Muller, Muller, Xavier, Dutkowski, Philipp, Andrea Schlegel   +5 more
core   +1 more source

Improved Normothermic Machine Perfusion After Short Oxygenated Hypothermic Machine Perfusion of Ischemically Injured Porcine Kidneys [PDF]

, 2021
Background: In an era where global kidney shortage has pushed the field of transplantation towards using more marginal donors, modified kidney preservation techniques are currently being reviewed.
Møldrup, Ulla, Lewis, Kate R., Hunter, James P., Pool, Merel B.F., Baan, Carla C., Leuvenink, Henri G D, Rozenberg, Kaithlyn M, Lohmann, Stine, Krag, Søren, Lewis, Kate R, Rozenberg, Kaithlyn M., Pool, Merel B F; id_orcid, Moers, Cyril; id_orcid, Eijken, Marco, Lignell, Stina, Jespersen, Bente, Moers, Cyril, Keller, Anna Krarup, Leuvenink, Henri G D; id_orcid, Ploeg, Rutger J, Hunter, James P, Baan, Carla C, Møller, Bjarne Kuno, Pool, Merel B F, Leuvenink, Henri G.D., Ploeg, Rutger J.   +25 more
core   +3 more sources

Hypothermic Machine Perfusion Preservation of the DCD Kidney: Machine Effects [PDF]

, 2013
Purpose. Kidneys from DCD donors represent a significant pool, but preservation problems exist. The study objective was to test the importance of machine type for hypothermic preservation of DCD kidneys. Methods.
Lindell, Susanne L., John Brassil, Heather Muir, Muir, Heather, Martin J. Mangino, Brassil, John, Mangino, Martin J., Susanne L. Lindell   +7 more
core   +1 more source

Is 2 h of Hypothermic Machine Perfusion for Pancreas Preservation Effective in Improving Graft Reperfusion? [PDF]

Transplant Direct
International audienceBackground: Static cold storage (SCS) remains the standard method for organ preservation. The development of parenchymal edema during prolonged hypothermic machine perfusion (HMP) was a major barrier to the introduction of this ...
Mesnard B, Masset C, Ogbemudia E, Bruneau S, Elzawahry M, Le Bas-Bernardet S, Minault D, Hervouet J, Cantarovich D, Rigaud J, Badet L, Friend P, Ploeg R, Blancho G, Hunter J, Prudhomme T, Branchereau J.   +16 more
europepmc   +2 more sources

First report of successful transplantation of a pediatric donor liver graft after hypothermic machine perfusion [PDF]

, 2019
One of the main limiting factors in pediatric liver transplantation is donor availability. For adults, DCD liver grafts are increasingly used to expand the donor pool.
Otto B. van Leeuwen, Yvonne de Vries, Scheenstra, René, Werner, Maureen J.M., de Jong, Iris E.M., Luhker, Olaf C., Robert J. Porte, de Jong, Iris E.M.; id_orcid, Iris E. M. de Jong, Frank A. J. A. Bodewes, de Kleine, Ruben H.J., Masato Fujiyoshi, van Leeuwen, Otto B., de Kleine, Ruben H.J.; id_orcid, Fujiyoshi, Masato, de Vries, Yvonne, René Scheenstra, Maureen J. M. Werner, Bodewes, Frank A.J.A., Ruben H. J. de Kleine, Olaf C. Luhker, Porte, Robert J.   +21 more
core   +2 more sources

Delivery of Mesenchymal Stem Cells during Hypothermic Machine Perfusion in a Translational Kidney Perfusion Study. [PDF]

Int J Mol Sci
In transplantation, hypothermic machine perfusion (HMP) has been shown to be superior to static cold storage (SCS) in terms of functional outcomes. Ex vivo machine perfusion offers the possibility to deliver drugs or other active substances, such as ...
Vallant N, Wolfhagen N, Sandhu B, Hamaoui K, Papalois V.   +4 more
europepmc   +2 more sources