Hypothermic Oxygenated Machine Perfusion of the Human Donor Pancreas [PDF]
Background: Transplantation of beta cells by pancreas or islet transplantation is the treatment of choice for a selected group of patients suffering from type 1 diabetes mellitus.
Lier, G +30 more
core +2 more sources
Hypothermic Machine Preservation of the Liver: State of the Art [PDF]
Purpose of Review: In this review, we highlight which livers may benefit from additional treatment before implantation and describe the concept of hypothermic machine liver perfusion.
Philipp Dutkowski +5 more
core +1 more source
Advances in Hypothermic and Normothermic Perfusion in Kidney Transplantation [PDF]
Hypothermic and normothermic machine perfusion in kidney transplantation are purported to exert a beneficial effect on post-transplant outcomes compared to the traditionally used method of static cold storage. Kidney perfusion techniques provide a window
Thomas B. Smith +2 more
core +4 more sources
Experimental study on coronary perfusion with selective brain cooling for direct aortic surgery [PDF]
1. Retrograde coronary perfusion in combination with selective brain cooling by irrigation was investigated in dogs, in comparison with direct coronary artery perfusion. 2.
Hayashi, Naomi
core +1 more source
Improved perfusion in hypothermic machine preservation of the liver. [PDF]
Introduction: Hypothermic machine perfusion (HMP) provides a better protectionagainst ischemic kidney damage compared to cold-storage (CS). A switch from static CS to HMP in liver transplantation could prevent Ischemic-Type-Biliary-Lesions due to ...
't Hart, Nils A. +19 more
core +1 more source
Hypothermic Machine Perfusion in Liver Transplantation [PDF]
Dynamic preservation strategies are a promising option to improve graft quality before transplantation, and to extend preservation time for either logistic or treatment reasons.
Schlegel, A +12 more
core +2 more sources
Monitoring Mitochondrial Function With High‐Resolution Respirometry During Ex‐Situ Heart Perfusion
Normothermic ESHP preserves mitochondrial respiratory function over 6 h in a porcine model (n = 6): OXPHOS capacities across NADH‐, fatty‐acid‐, and succinate‐linked pathways remain stable, with reduced cytochrome‐c control efficiency indicating improved outer‐membrane integrity. HRR provides a rapid, actionable readout for organ assessment.
Lukas Stastny +12 more
wiley +1 more source
Experimental Extracorporeal Circulation System: A Pilot Study in Rats
A miniature extracorporeal circulation (ECC) system was developed for reproducible rodent studies. This system incorporates an integrated heat exchanger and a silicone membrane oxygenator within a double‐lumen circuit, resulting in an ultralow priming volume of < 1.5 mL.
Akira T. Kawaguchi +7 more
wiley +1 more source
Hypothermic machine perfusion in kidney transplantation: back to the future? [PDF]
Static cold storage is currently the most used method of organ preservation worldwide. However, cutting edge technology and dramatic changes in the donor pattern have lately renewed the interest toward hypothermic machine perfusion.
M. Ferraresso, E. Favi
core +1 more source
Progress Toward a Portable Artificial Lung: A Systematic Review
Eight portable respiratory assist devices were identified. The CE‐marked MobyBox and the FDA‐approved Breethe OXY‐1 system are in clinical use. Each device is substantially minimized to allow ambulation, but further work is required to address challenges related to anticoagulant management and safe mobilization. Created in BioRender. Svendsen, A. (2026)
Maja Munk Svendsen +5 more
wiley +1 more source

