Results 41 to 50 of about 193,493 (202)

HYPOTHERMIC PERFUSION OF THE KIDNEY: FROM RESEARCH TO CLINICAL PRACTICE

, 2023
Kidney transplantation is the treatment of choice for patients with end stage renal disease (ESRD). Donor availability is lower than demand, therefore suboptimal grafts retrieved from donors after brain death with expanded criteria ...
Busutti, Marco, Ravaioli, Matteo, La Manna, Gaetano, Fallani, Guido, Radi, Giorgia, Germinario, Giuliana   +5 more
core   +1 more source

The impact on the bioenergetic status and oxidative-mediated tissue injury of a combined protocol of hypothermic and normothermic machine perfusion using an acellular haemoglobin-based oxygen carrier: The cold-to-warm machine perfusion of the liver.

PLoS ONE, 2019
INTRODUCTION:The combination of hypothermic and normothermic machine perfusion (HMP+NMP) of the liver provides individual benefits of both techniques, improving the rescue of marginal organs.
Yuri L Boteon, Richard W Laing, Andrea Schlegel, Lorraine Wallace, Amanda Smith, Joseph Attard, Ricky H Bhogal, Gary Reynolds, M Thamara PR Perera, Paolo Muiesan, Darius F Mirza, Hynek Mergental, Simon C Afford   +12 more
doaj   +1 more source

Machine Perfusion of Livers with Moderate Macrosteatosis: Efficacy of HOPE with Controlled Rewarming

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Objective. To evaluate the efficacy of machine perfusion using hypothermic oxygenated perfusion (HOPE) with controlled rewarming in reducing ischemia-reperfusion injury of human donor livers with moderate macrosteatosis through comprehensive analysis of ...
B. I. Yaremin, M. S. Novruzbekov, A. G. Balkarov, B. I. Kazymov, E. Yu. Anosova, P. O. Svishcheva, O. N. Pavlova, S. M. Khanova   +7 more
doaj   +3 more sources

Current perspectives in transplant medicine: hypothermic oxygenated perfusion

Transplant Research and Risk Management, 2016
Sebastian G Michel,1 Joren C Madsen2,3 1Department of Cardiac Surgery, Ludwig-Maximilians-University, Munich, Germany; 2Department of Surgery, Center for Transplantation Sciences, 3Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA Abstract: The purpose of this review was to provide an update on ...
Michel,Sebastian, Madsen,Joren
  +7 more sources

Uterine Transplant Optimization From a Preclinical Donor Model With Controlled Cardiocirculatory Arrest

Transplantation Direct
Background. Uterus transplantation from deceased donors offers a promising solution to the organ shortage, but optimal preservation methods are crucial for successful outcomes. Our primary objective is to conduct an initial assessment of the contribution
Emma Loiseau, MSc, Benoit Mesnard, MSc, Sarah Bruneau, PhD, Carla De Sousa, MD, Stéphanie Bernardet, PhD, Jeremy Hervouet, David Minault, Stephan Levy, MSc, Antoine Le Gal, MD, Ludivine Dion, PhD, Gilles Blancho, MD, PhD, Vincent Lavoue, MD, PhD, Julien Branchereau, MD, PhD   +12 more
doaj   +1 more source

Effluent Molecular Analysis Guides Liver Graft Allocation to Clinical Hypothermic Oxygenated Machine Perfusion

Biomedicines, 2021
Hypothermic-oxygenated-machine-perfusion (HOPE) allows assessment/reconditioning of livers procured from high-risk donors before transplantation. Graft referral to HOPE mostly depends on surgeons’ subjective judgment, as objective criteria are still ...
Caterina Lonati, Andrea Schlegel, Michele Battistin, Riccardo Merighi, Margherita Carbonaro, Paola Dongiovanni, Patrizia Leonardi, Alberto Zanella, Daniele Dondossola   +8 more
doaj   +1 more source

Machine Perfusion of Donation After Circulatory Death Liver and Lungs Before Combined Liver-lung Transplantation

Transplantation Direct, 2021
Shortage of deceased donor organs for transplantation has led to the increased use of organs from donation after circulatory death (DCD) donors. There are currently no reports describing outcomes after multiorgan transplantation with DCD livers.
Otto B. van Leeuwen, PhD, Isabel M.A. Brüggenwirth, BSc, Ruben H.J. de Kleine, MD, Aad P. van den Berg, MD, PhD, Erik A.M. Verschuuren, MD, PhD, Michiel E. Erasmus, MD, PhD, Robert J. Porte, MD, PhD   +6 more
doaj   +1 more source

Optimization of Oxygen Supply Conditions for Hypothermic Oxygenated Machine Perfusion

Transplantation Proceedings
Hypothermic oxygenated machine perfusion (MP) contributes to the reduction of delayed graft function and ischemic reperfusion injury in donated after circulatory death donors. In this study, we focused on perfusate temperature, oxygen consumption, and oxygen supply and proposed the possibility of assessing organ function.
Tomoki Abe, Masafumi Furukawa, Naoto Matsuno, Seisuke Sakamoto, Hiromichi Obara   +4 more
openaire   +2 more sources

Role of oxygen during hypothermic machine perfusion preservation of the liver

Transplant International, 2010
Grafts from non-heart-beating donors are thought to be best preserved by hypothermic machine perfusion (HMP). Controversy exists concerning the role of oxygenation during HMP. In this study, we wanted to evaluate the relative role of oxygenation for graft integrity during and after HMP.
Lüer, Bastian, Koetting, Martina, Efferz, Patrik, Minor, Thomas   +3 more
openaire   +2 more sources

Comment on Sun et al. First Experience with Hypothermic Oxygenated Perfusion in Human Uteri: Feasibility and Metabolic Characterization. J. Clin. Med. 2026, 15, 2820 [PDF]

J Clin Med
International audienceWe read with great interest the recent article by Sun et al. describing the first application of hypothermic oxygenated perfusion (HOPE) in human uteri, titled “First Experience with Hypothermic Oxygenated Perfusion in Human Uteri ...
Sousa, C., Dion, Ludivine, Dugast, Margot, Lavoué, Vincent   +3 more
europepmc   +2 more sources