Results 31 to 40 of about 193,493 (202)

Reply to: “The importance of adequate oxygenation during hypothermic machine perfusion” [PDF]

JHEP Reports, 2021
International ...
Val-Laillet, David, Ben Mosbah, Ismaïl, Corlu, Anne, Boudjema, Karim   +3 more
openaire   +5 more sources

Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial [PDF]

, 2021
BACKGROUND: Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures.
de Meijer, V.E., de Jonge, J., Erdmann, Joris I, Jochmans, Ina, de Haas, Robbert J, Slangen, Jules J G, Cerisuelo, M.C., Monbaliu, D., Schurink, Ivo J., van Hoek, Bart, de Meijer, Vincent E; id_orcid, Schurink, Ivo J, Gilbo, Nicholas, Jonge, J. de, Heaton, Nigel, van Hoek, B., Huurman, Volkert A L, Huurman, Volkert A.L., Jochmans, I., Slangen, J.J.G., Troisi, Roberto I., Cerisuelo, M. Cortes, Polak, W.G., van Leeuwen, Otto B, van Leeuwen, O.B., van Leeuwen, Otto B., de Haas, Robbert J., Porte, R.J., Meijer, V.E. de, Murad, S. Darwish, de Vries, Y., van den Berg, A.P., Huurman, V.A.L., Slangen, Jules J.G., Polak, Wojciech G, van Rijn, Rianne, de Meijer, Vincent E, van den Berg, Aad P, Vries, Y. de, de Meijer, Vincent E., Porte, Robert J, van den Berg, Aad P., Schurink, I.J., de Haas, R.J., Erdmann, Joris I., de Vries, Yvonne, Hoek, B. van, Heaton, N., de Jonge, Jeroen, Berg, A.P. van den, Haas, R.J. de, Darwish Murad, Sarwa, DHOPE DCD Trial Investigators, Murad, Sarwa Darwish, Vanlander, Aude, Slangen, J.JG., Cerisuelo, Miriam Cortes, Gilbo, N., Rijn, R. van, Van Rijn, R., Murad, S.D., Leeuwen, O.B. van, Erdmann, J.I., Polak, Wojciech G., Huurman, V.AL., Vanlander, A., Troisi, R.I., Cortes Cerisuelo, Miriam, Troisi, Roberto I, Porte, Robert J., Monbaliu, Diethard   +70 more
core   +3 more sources

Preservation of Donor Hearts Using Hypothermic Oxygenated Perfusion [PDF]

Annals of Transplantation, 2014
Hypothermic machine perfusion of donor hearts enables continuous aerobic metabolism and washout of toxic metabolic byproducts. We evaluated the effect of machine perfusion on cardiac myocyte integrity in hearts preserved for 4 h in a novel device that provides pulsatile oxygenated hypothermic perfusion (Paragonix Sherpa Perfusion™ Cardiac Transport ...
Sebastian G, Michel, Glenn M, La Muraglia, Maria Lucia L, Madariaga, James S, Titus, Martin K, Selig, Evan A, Farkash, James S, Allan, Lisa M, Anderson, Joren C, Madsen   +8 more
openaire   +2 more sources

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Establishment and assessment of pancreas preservation using oxygenated hypothermic machine perfusion [PDF]

, 2022
Background: Pancreatic transplantation is the treatment of choice for a selected group of patients with the most severe complications of diabetes. The two main causes of early failure in this transplant are pancreatitis and venous graft thrombosis.
Hakim, Gabriella
core   +1 more source

Prolonged Normothermic Ex Vivo Kidney Perfusion Is Superior to Cold Nonoxygenated and Oxygenated Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts

Transplantation Direct, 2021
Background. The increased usage of marginal grafts has triggered interest in perfused kidney preservation to minimize graft injury. We used a donation after circulatory death (DCD) porcine kidney autotransplantation model to compare 3 of the most ...
Laura I. Mazilescu, MD, Peter Urbanellis, MD, MSc, Moritz J. Kaths, MD, MSc, Sujani Ganesh, MSc, Toru Goto, MD, Yuki Noguchi, MD, PhD, Rohan John, MD, Ana Konvalinka, MD, PhD, Istvan Mucsi, MD, PhD, Anand Ghanekar, MD, PhD, Darius J. Bagli, MD, MSc, Julie Turgeon, PhD, Annie Karakeusian Rimbaud, BSc, Marie-Josée Hébert, MD, Mélanie Dieudé, PhD, Isabelle Alleys, PhD, Etienne Dore, MSc, Eric Boilard, PhD, Herman S. Overkleeft, PhD, Lianne I. Willems, PhD, Lisa A. Robinson, MD, Markus Selzner, MD   +21 more
doaj   +1 more source

Hypothermic oxygenated machine perfusion of the human pancreas for clinical islet isolation: a prospective feasibility study [PDF]

, 2021
Due to an increasing scarcity of pancreases with optimal donor characteristics, islet isolation centers utilize pancreases from extended criteria donors, such as from donation after circulatory death (DCD) donors, which are particularly susceptible to ...
Engelse, M.A., Doppenberg, J.B., Krikke, Christina, Doppenberg, Jason B., Krikke, C., Engelse, Marten A., Leuvenink, Henri G. D.; id_orcid, de Koning, Eelco J. P., Leuvenink, H.G.D., Leuvenink, Henri G. D., Koning, E.J.P. de, Leemkuil, M., Leemkuil, Marjolein   +12 more
core   +2 more sources

Ex Situ Dual Hypothermic Oxygenated Machine Perfusion for Human Split Liver Transplantation

Transplantation Direct, 2021
Background. Liver splitting allows the opportunity to share a deceased graft between 2 recipients but remains underutilized. We hypothesized that liver splitting during continuous dual hypothermic oxygenated machine perfusion (DHOPE) is feasible, with ...
Adam M. Thorne, BSc, Veerle Lantinga, BSc, Silke Bodewes, BSc, Ruben H. J. de Kleine, MD, Maarten W. Nijkamp, MD, PhD, Joost Sprakel, MD, Hermien Hartog, MD, PhD, Wojciech G. Polak, MD, PhD, Robert J. Porte, MD, PhD, Vincent E. de Meijer, MD, PhD   +9 more
doaj   +1 more source

Hypothermic oxygenated machine perfusion prevents arteriolonecrosis of the peribiliary plexus in pig livers donated after circulatory death. [PDF]

PLoS ONE, 2014
BackgroundLivers derived from donation after circulatory death (DCD) are increasingly accepted for transplantation. However, DCD livers suffer additional donor warm ischemia, leading to biliary injury and more biliary complications after transplantation.
Sanna Op den Dries, Michael E Sutton, Negin Karimian, Marieke T de Boer, Janneke Wiersema-Buist, Annette S H Gouw, Henri G D Leuvenink, Ton Lisman, Robert J Porte   +8 more
doaj   +1 more source