Results 61 to 70 of about 248,739 (243)

Can weak lensing surveys confirm BICEP2 ? [PDF]

, 2014
The detection of B-modes in the Cosmic Microwave Background (CMB) polarization by the BICEP2 experiment, if interpreted as evidence for a primordial gravitational wave background, has enormous ramifications for cosmology and physics.
Chisari, Nora Elisa, Dvorkin, Cora, Schmidt, Fabian   +2 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Efficacy and safety of six Chinese patent medicines for elderly functional constipation: a network meta-analysis

Frontiers in Medicine
BackgroundFunctional constipation (FC) is a prevalent condition in the elderly that greatly reduces quality of life. Combined treatment using Chinese Patent Medicine (CPM) and Western Medicine (WM) is frequently employed; however, the comparative ...
Xinyu Wang, Min Wang, Guishan Liu, Riming Zhong, Lei Liu, Qiuming Chen, Rui Li   +6 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Problem Behaviours and Relinquishment: Challenges Faced by Clinical Animal Behaviourists When Assessing Fear and Frustration

Animals
Fear and frustration are two emotions thought to frequently contribute to problem behaviour, often leading to relinquishment. Inferring these emotions is challenging as they may present with some similar general signs, but they potentially require ...
Beverley M. Wilson, Carl D. Soulsbury, Daniel S. Mills   +2 more
doaj   +1 more source

The High-Order-Multiplicity of Unusually Wide M-dwarf Binaries: Eleven New Triple and Quadruple Systems

, 2010
M-dwarfs in extremely wide binary systems are very rare, and may thus have different formation processes from those found as single stars or close binaries in the field.
A. A. West, A. Kraus, Abazajian, Artigau, Baraffe, Bergfors, Bochanski, Bodenheimer, Burgasser, Close, Dhital, Faherty, K. G. Stassun, Konopacky, Kraus, Kraus, Kraus, Law, Mason, Munn, Munn, N. M. Law, Offner, Phan-Bao, Radigan, Reid, Reid, Reipurth, S. Dhital, Siegler, York   +30 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Syrian civil war and assessment of tuberculosis among Syrian refugees and local citizens in Mardin

Frontiers in Public Health
BackgroundWe compared tuberculosis (TB) characteristics and outcomes between Syrian refugees and local citizens in Mardin, Turkey (2016–2023), a border province with substantial population mobility.MethodsRetrospective, registry-based cross-sectional ...
Barış Çil, Mehmet Kabak, Mehmet Sinan Bodur, Erkan Sanmak, Güldan Güneş, Yusuf Alakaş, Nicolai Savaskan, Hamdiye Turan, Hamza Oktay   +8 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

A Frequent Misuse of Significance Tests [PDF]

Economists sometimes interpret the failure of a significance test to disconfirm a hypothesis as evidence that this hypothesis is valid. Six examples of this are cited from recent journals.
Thomas Mayer
core   +3 more sources