Results 21 to 30 of about 1,126 (117)

Sequential assessment of clinical and laboratory parameters in patients with hemorrhagic fever with renal syndrome. [PDF]

PLoS ONE, 2018
BACKGROUND:Information on the sequential appearance, duration, and magnitude of clinical and laboratory parameters in hemorrhagic fever with renal syndrome (HFRS) is limited.
Emil Pal, Miša Korva, Katarina Resman Rus, Nataša Kejžar, Petra Bogovič, Anica Kurent, Tatjana Avšič-Županc, Franc Strle   +7 more
doaj   +1 more source

Transient idiopathic central diabetes insipidus: is severe sepsis a possible cause?

Italian Journal of Medicine, 2017
Idiopathic central diabetes insipidus (CDI) is a disorder characterized by hypotonic polyuria and polydipsia, without any identified etiology. Here we report a case of a 57-year-old woman, with idiopathic CDI, admitted to our department with severe ...
Ilaria Lazzari, Alessandro Graziani, Federica Mirici, Giuseppe Francesco Stefanini   +3 more
doaj   +1 more source

Federal clinical guidelines on diagnosis and treatment of diabetes insipidus in adults

Ожирение и метаболизм, 2018
We do not recommend population screening for diabetes insipidus (DI) (B3). We recommend to perform diagnostic testing for central diabetes insipidus (CDI) in patients who underwent neurosurgery, after skull and brain trauma, subarchnoid hemorrhage (B3 ...
Ivan I. Dedov, Galina A. Mel'nichenko, Ekaterina A. Pigarova, Larisa K. Dzeranova, Liudmila Y. Rozhinskaya, Elena G. Przhiyalkovskaya, Zhanna E. Belaya, Andrey Y. Grigoriev, Alexander V. Vorontsov, Alexander S. Lutsenko, Ludmila I. Astafyeva   +10 more
doaj   +1 more source

POSTOPERATIVE RISE IN SERUM SODIUM LEVEL, INDICATOR OF DIABETES INSIPIDUS AFTER PITUITARY ADENOMA SURGERY

Pakistan Armed Forces Medical Journal, 2019
Objective: To study the efficacy of post operative rise in serum sodium level as indicator of diabetes insipidus after pituitary adenoma surgery.
Noor-ul-Huda Maria, Qurrat-Ul-Ain ., Muhammed Anwar   +2 more
doaj   +4 more sources

Juvenile-onset gout and adipsic diabetes insipidus: A case report and literature review

Journal of International Medical Research, 2018
The prevalence of juvenile-onset gout has been increasing. Hereditary factors and secondary diseases should be considered in these patients. Adipsic diabetes insipidus (ADI) is characterized by arginine vasopressin (AVP) deficiency, which results in ...
Yun Zhang, Dongmei Wang, Yiding Feng, Wen Zhang, Xuejun Zeng   +4 more
doaj   +1 more source

Broadening horizons: Pathogenesis and therapeutics of renal ciliopathies

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
This review elucidates the molecular mechanisms and aberrant signaling pathways in renal ciliopathies, links genetic heterogeneity to clinical phenotypes, and lays a theoretical basis for prenatal diagnosis and novel therapies. Abstract Renal ciliopathies encompass a spectrum of genetic disorders arising from structural or functional impairments of ...
Qiaowei Zhang, Shuwen Xue, Zhi Gao, Panlai Shi, Li Wang, Qi Feng, Xiangdong Kong, Xiaofan Zhu   +7 more
wiley   +1 more source

An Optimized Diagnostic Approach for Adults With Suspected Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
A multidisciplinary strategy that integrates deep phenotyping with expert genetic interpretation substantially increases the likelihood of reaching a diagnosis in adults suspected of having an IMD. ABSTRACT Inherited metabolic disorders (IMDs) arise from defects in metabolic pathways essential for normal biochemical function.
Machteld M. Oud, Elise A. Ferreira, Clara D. M. van Karnebeek, Robin Wijngaard, Nicole I. Wolf, Marc Engelen, Mareen Datema, Sacha Ferdinandusse, André B. P. van Kuilenburg, Laura Steinbusch, Saskia N. van der Crabben, Mirjam Langeveld, on behalf of the ZOEMBA Study Group   +12 more
wiley   +1 more source

Open‐Label, Balanced, Randomized, Single‐Dose, Three‐Treatment, Three‐Sequence, Three‐Period, Three‐Way Crossover Oral Bioequivalence Study of Desmopressin Acetate Oral Solution

Clinical Pharmacology in Drug Development, Volume 15, Issue 8, August 2026.
ABSTRACT Desmopressin is first‐line therapy for central diabetes insipidus, also known as arginine vasopressin deficiency, but presents dosing challenges due to its narrow therapeutic index. This open‐label, randomized, three‐way crossover study evaluated the bioequivalence of a new desmopressin acetate oral solution (50 mcg/mL) compared to ...
Adam Christensen, Axay Parth, Mansi Kotak, Danka Radosavjevic, Catherine Gorman Moore, Byung‐Woun Seo   +5 more
wiley   +1 more source

Genetic Insights Into AVP Deficiency: Identification of a Novel AVP Variant and Compilation of a Curated Catalogue of Pathogenic Variants

Clinical Genetics, Volume 110, Issue 2, Page 203-209, August 2026.
We identified a novel pathogenic AVP variant in two Danish families with autosomal dominant inheritance of symptoms of AVP deficiency. In addition, we compiled a catalogue of additionally 109 AVP variants that cause AVP deficiency and demonstrated the advantage of combining expert‐assisted curation, literature search, and online repositories to ensure ...
Jennifa Joseph, Esben Søndergaard, Sine Knorr, Jane Hagelskjær Knudsen, Søren Rittig, Jane Hvarregaard Christensen   +5 more
wiley   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source