Transient severe hypotonic hyponatraemia in children – presentation of three cases
Hyponatraemia, defined as sodium concentration below 135 mmol/l, is one of the most common electrolyte imbalances. Differential diagnosis of hyponatraemia is difficult.
Joanna A. Chrzanowska +4 more
doaj +2 more sources
Severe Diabetic Ketoacidosis With Refractory Hypernatremia due to Hypokalemia-Induced Arginine Vasopressin Resistance: A Case Report and Literature Review. [PDF]
Diabetic ketoacidosis (DKA) is a life‐threatening complication of diabetes characterized by hyperglycemia, high‐anion‐gap metabolic acidosis, and ketonemia. Hypernatremia in DKA is uncommon and typically reflects disproportionate free water loss. Arginine vasopressin resistance (AVP‐R), previously known as nephrogenic diabetes insipidus, may occur in ...
Shihab R +4 more
europepmc +2 more sources
Severe Transient Central Diabetes Insipidus After Pituitary Adenoma Removal With Peak Urine Output of 33.5 L in 24 h. [PDF]
Background Postoperative central diabetes insipidus (CDI) is a well‐documented but often transient complication following transsphenoidal surgery (TSS) for pituitary adenomas. CDI is characterized by excessive urine output due to impaired antidiuretic hormone (ADH) secretion following damage to the neurohypophyseal stalk or hypothalamus.
Bhandari G +3 more
europepmc +2 more sources
Infant Nephrogenic Diabetes Insipidus: Challenges Leading to Delayed Management. [PDF]
Background Nephrogenic diabetes insipidus (NDI) is a rare, potentially life‐threatening renal tubular disorder characterized by a decreased ability to concentrate urine due to antidiuretic hormone (ADH) resistance, leading to significant free water loss.
Stankovic M S +10 more
europepmc +2 more sources
Genetic Insights Into AVP Deficiency: Identification of a Novel AVP Variant and Compilation of a Curated Catalogue of Pathogenic Variants. [PDF]
We identified a novel pathogenic AVP variant in two Danish families with autosomal dominant inheritance of symptoms of AVP deficiency. In addition, we compiled a catalogue of additionally 109 AVP variants that cause AVP deficiency and demonstrated the advantage of combining expert‐assisted curation, literature search, and online repositories to ensure ...
Joseph J +5 more
europepmc +2 more sources
Polyuria in a patient on chronic lithium therapy: a case report and literature review
Lithium (Li) has been associated with several forms of renal injury, the most prevalent being impaired urinary concentrating ability, which is reported in individuals on chronic lithium therapy.
C. J. Subasinghe +2 more
doaj +1 more source
Managing polyuria during lithium treatment: a preliminary prospective observational study [PDF]
Objectives:Lithium-treated patients with polyuria are at increased risk of lithium toxicity. We aimed to describe the clinical benefits and risks of different management strategies for polyuria in community lithium-treated patients.Methods:This is a ...
Kinahan, James C. +4 more
core +1 more source
Analysis of salmonid leukocytes purified by hypotonic lysis of erythrocytes [PDF]
A technique that uses hypotonic lysis of erythrocytes was optimized for the purification of leukocytes from the peripheral blood and anterior kidney (pronephros) of rainbow trout Oncorhynchus mykiss. Comparisons of initial blood dilution (1:2, 1:4, and 1:
Schreck, Carl B. +5 more
core +6 more sources
A Partial Phenotype of adFNDI Related to the Signal Peptide c.55G>A Variant of the AVP Gene
The autosomal dominant familial form of neurohypophyseal diabetes insipidus (adFNDI) is a rare inherited endocrine disorder characterized by hypotonic polyuria, severe thirst and polydipsia, which results from a deficient neurosecretion of the ...
Vera Tocci +10 more
doaj +1 more source
Nocturnal polyuria and nocturia
BACKGROUND: Nocturia is a common complaint that can have a significant impact on quality of life. The pathophysiology is usually multifactorial and can be due to poor sleep, nocturnal polyuria, or low bladder capacity alone or in combination.
Shachi Tyagi +3 more
core +1 more source

