Transient Postoperative Diabetes Insipidus With Hypovolemic Shock Temporally Associated With Dexmedetomidine, Propofol, and Sevoflurane: A Case Report [PDF]
Dexmedetomidine, propofol, and sevoflurane are widely used anesthetic agents, but reports of water metabolism disturbances—particularly drug‐induced diabetes insipidus (DI)—associated with their use remain extremely rare.
Yuan Meng +6 more
doaj +3 more sources
Approach to the Patient With Suspected Hypotonic Polyuria
Abstract Investigation and management of hypotonic polyuria is a common challenge in clinical endocrinology. The 3 main causes, recently renamed to arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus), arginine vasopressin resistance (AVP-R, formerly nephrogenic diabetes insipidus), and primary polydipsia (PP ...
Mark Gurnell +2 more
exaly +5 more sources
Severe Diabetic Ketoacidosis With Refractory Hypernatremia due to Hypokalemia-Induced Arginine Vasopressin Resistance: A Case Report and Literature Review. [PDF]
Diabetic ketoacidosis (DKA) is a life‐threatening complication of diabetes characterized by hyperglycemia, high‐anion‐gap metabolic acidosis, and ketonemia. Hypernatremia in DKA is uncommon and typically reflects disproportionate free water loss. Arginine vasopressin resistance (AVP‐R), previously known as nephrogenic diabetes insipidus, may occur in ...
Shihab R +4 more
europepmc +2 more sources
Severe Transient Central Diabetes Insipidus After Pituitary Adenoma Removal With Peak Urine Output of 33.5 L in 24 h. [PDF]
Background Postoperative central diabetes insipidus (CDI) is a well‐documented but often transient complication following transsphenoidal surgery (TSS) for pituitary adenomas. CDI is characterized by excessive urine output due to impaired antidiuretic hormone (ADH) secretion following damage to the neurohypophyseal stalk or hypothalamus.
Bhandari G +3 more
europepmc +2 more sources
Infant Nephrogenic Diabetes Insipidus: Challenges Leading to Delayed Management. [PDF]
Background Nephrogenic diabetes insipidus (NDI) is a rare, potentially life‐threatening renal tubular disorder characterized by a decreased ability to concentrate urine due to antidiuretic hormone (ADH) resistance, leading to significant free water loss.
Stankovic M S +10 more
europepmc +2 more sources
Central and nephrogenic diabetes insipidus: updates on diagnosis and management [PDF]
Diabetes insipidus (DI) is a rare endocrine disease involving antidiuretic hormone (ADH), encompassing both central and nephrogenic causes. Inability to respond to or produce ADH leads to inability of the kidneys to reabsorb water, resulting in hypotonic
Kathryn Flynn +4 more
doaj +2 more sources
Rapid-onset hypernatremia induced by central diabetes insipidus leading to osmotic demyelination syndrome: a case report [PDF]
This case study describes a middle-aged male patient who developed persistent hypernatremia due to central diabetes insipidus (CDI), presenting with polyuria (up to 8.5 L/24 h), polydipsia, and hypotonic urine (urine specific gravity < 1.005).
Yifan Zhang +5 more
doaj +2 more sources
Arginine Vasopressin (AVP) Deficiency: Diagnosis and Treatment – An Update [PDF]
The hypothalamo-neurohypophysial axis comprises magnocellular neurons in the supraoptic and paraventricular nuclei that traffic arginine vasopressin (AVP) and oxytocin (OXT) to the posterior pituitary for systemic release.
Mirjam Christ-Crain
doaj +2 more sources
Partial central diabetes insipidus during lithium use: A case report and literature review. [PDF]
Abstract Background Nephrogenic diabetes insipidus (NDI) is a well‐known adverse effect of lithium, which occurs in approximately 20%–40% of long‐term lithium users. Although rare, there have been reports of central diabetes insipidus (CDI) associated with lithium use.
Ichinose M +9 more
europepmc +2 more sources
Abstract Hypotonic polyuria, also known as the polyuria-polydipsia syndrome (PPS), caused by primary polydipsia (PP), arginine vasopressin deficiency (AVP-D or central diabetes insipidus), or uncommonly by AVP resistance (AVP-R), is diagnostically challenging due to overlapping symptoms and the need to conclusively diagnose or exclude ...
Christine March
exaly +3 more sources

