Results 71 to 80 of about 16,203 (292)

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

open access: yesAdvanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret   +6 more
wiley   +1 more source

Hypotonic solutions induce epithelium-dependent relaxation of isolated canine bronchi

open access: yes, 1992
The present study was designed to investigate the effect of changes in osmolarity on the modulatory role of the respiratory epithelium on the underlying smooth muscle. Canine bronchial segments with or without epithelium were perfused intraluminally with
Gao, Y, Vanhoutte, PM
core  

Effect of collagenase and ouabain on renal cell volume in hypotonic media

open access: yes, 1980
Proximal straight tubules (S2 segments) swell rapidly in hypotonic media, but within a few minutes their volume returns toward control levels due to extrusion of K, Na, Cl, and water from the cytoplasm. In the present studies we determined the extent to
M. A. Linshaw, J. J. Grantham
core   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

open access: yesAdvanced Healthcare Materials, EarlyView.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka   +2 more
wiley   +1 more source

Dehydration in adults and old people

open access: yesEmergency Care Journal, 2007
Dehydration is a decrease in total body water, reflected in altered serum sodium, osmolality and BUN elevation. There are three types of dehydration: hypertonic, hypotonic and isotonic.
Ivo Casagranda   +3 more
doaj   +1 more source

Hypotonic and isotonic intravenous maintenance fluids in hospitalized controlled trial.

open access: yes, 2019
https://bmjpaedsopen.bmj.com/content/bmjpo/3/1/e000385.full.pdfAbstract Objective: To compare the changes in serum sodium and acid/base status in patients receiving hypotonic and isotonic solutions.
Siaba, Alejandro.   +5 more
core  

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

open access: yesAdvanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao   +7 more
wiley   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

open access: yesAdvanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi   +15 more
wiley   +1 more source

The Corrected Serum Sodium Concentration in Hyperglycemic Crises: Computation and Clinical Applications

open access: yesFrontiers in Medicine, 2020
In hyperglycemia, hypertonicity results from solute (glucose) gain and loss of water in excess of sodium plus potassium through osmotic diuresis. Patients with stage 5 chronic kidney disease (CKD) and hyperglycemia have minimal or no osmotic diuresis ...
Todd S. Ing   +6 more
doaj   +1 more source

The influence of hypotonic carbohydrate electrolyte solutions on muscle metabolism and exercise capacity with regards to intermittent high intensity shuttle running [PDF]

open access: yes, 2003
Performance and exercise capacity in prolonged continuous exercise has been shown to be enhanced by the ingestion of dilute (-6%) carbohydrate-electrolyte (CHO-E) solutions during exercise.
Foskett, Andrew, Andrew Foskett (551643)
core  

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