Results 91 to 100 of about 2,764,830 (288)

Effectiveness of Isotonic Resuscitation Fluid Compared with Hypotonic Solutions in Children with Septic Shock at H Adam Malik Hospital Medan

, 2023
Introduction Early fluid resuscitation is essential to stabilize tissue hypoperfusion and crystalloid is the mainstay of choice for resuscitation in septic shock.
Silviyani, Rahmi
core   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

Mechanical stability of individual bacterial cells under different osmotic pressure conditions: a nanoindentation study of Pseudomonas aeruginosa

Beilstein Journal of Nanotechnology
Nanomechanical maps to test the mechanical response of the outer envelope of Pseudomonas aeruginosa were obtained utilizing atomic force microscopy in force–volume mode in the low range of loading forces when exposed to hypotonic (Milli-Q water ...
Lizeth García-Torres, Idania De Alba Montero, Eleazar Samuel Kolosovas-Machuca, Facundo Ruiz, Sumati Bhatia, Jose Luis Cuellar Camacho, Jaime Ruiz-García   +6 more
doaj   +1 more source

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

Advanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang, Ting Shen, Yanfang Qiu, Wei Zhang, Ziran Zheng, Jiayi Sun, Yuedi Yao, Mianfeng Yao, Jiang Li   +8 more
wiley   +1 more source

Enteral electrolyte solutions with different osmolarities administered in a continuous flow in newborn calves

Ciência Rural
: This study compared the effects of enteral electrolyte solutions with different osmolarities in Holstein cattle. Eighteen newborn calves were evenly divided into three groups and administered the following treatments: hypotonic electrolyte solution ...
José Dantas Ribeiro Filho, Waleska de Melo Ferreira Dantas, Antônio de Pádua Lima, Rinaldo Batista Viana, Micheline Ozana da Silva, Pedro Ancelmo Nunes Ermita, Gláucia Matos Marques da Silva, Bruna Maria Ribeiro, Caio Monteiro Costa, Lorena Chaves Monteiro   +9 more
doaj   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Asymmetric Structure‐Driven Functional Synergy: A Multistimuli‐Activated Janus Nanomotor for Self‐Amplifying NO Cascade Therapy

Advanced Science, EarlyView.
The Janus nanomotors leverage an “asymmetric structure‐driven functional synergy” strategy to orchestrate spatiotemporally coordinated catalytic functions, in situ self‐amplifying NO generation, and deep tumor penetration, thereby enabling controllable, sustained, and uniform NO generation within the tumor microenvironment.
Chengcheng Li, Yu Zhang, Yu Chen, Lingyun He, Xian Shen, Weijian Sun, Hongbo Zhang   +6 more
wiley   +1 more source

Two enteral solutions with different chloride concentrations administered by naso-ruminal route for fluid therapy in adult cattle

Ciência Rural
: Six adult Holstein cows were used in this fluid therapy study. All animals were previously submitted to 24 hours of water and food abstaining period and submitted to both hydration treatments for eight hours in a crossover design 6x2.
Samuel Rodrigues Alves, Marcel Ferreira Bastos Avanza, Micheline Ozana da Silva, Pedro Ancelmo Nunes Ermita, Lidiany Lopes Gomes, Lorena Chaves Monteiro, Paulo Vinícius de Morais Santos, Caio Monteiro Costa, Gabriella Maria Morais Ferreira, Felipe Sperandio Mattos, José Dantas Ribeiro Filho   +10 more
doaj   +1 more source

A RNA-Seq Analysis of the Rat Supraoptic Nucleus Transcriptome: Effects of Salt Loading on Gene Expression.

PLoS ONE, 2015
Magnocellular neurons (MCNs) in the hypothalamo-neurohypophysial system (HNS) are highly specialized to release large amounts of arginine vasopressin (Avp) or oxytocin (Oxt) into the blood stream and play critical roles in the regulation of body fluid ...
Kory R Johnson, C C T Hindmarch, Yasmmyn D Salinas, YiJun Shi, Michael Greenwood, See Ziau Hoe, David Murphy, Harold Gainer   +7 more
doaj   +1 more source