Results 141 to 150 of about 92,945 (337)

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

open access: yesThe FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Possibilities of the use of fast scan voltammetry in simultaneous determination of purines at carbon fiber ultramicroelectrodes

open access: yesJournal of the Brazilian Chemical Society, 2000
Hypoxanthine, xanthine and uric acid are purines present in extracellular fluids that can be used as metabolic markers, in evaluation of meat conservation and other applications. Voltammetric studies were performed in order to investigate the possibility
Cavalheiro Éder T. G.   +2 more
doaj  

Phosphoproteomic Reveals That Phosphoglycerate Kinase 2 Suppresses Hypoxanthine Accumulation in Broiler

open access: yesFood Frontiers
Recent studies have found that the amount and proportion of meat flavor–related metabolites differ among different parts of muscle, which is partly attributed to their diverse myofiber type composition.
Manting Ma   +6 more
doaj   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

open access: yesJournal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann   +8 more
wiley   +1 more source

Validade comercial de sardinhas inteiras e refrigeradas avaliada por análises físico-químicas, bacteriológicas e sensorial Shelf life of chilled and whole sardines evaluated by physical-chemical, bacteriological and sensory

open access: yesCiência Rural, 2012
A validade comercial de sardinhas das espécies Sardinella brasiliensis e Cetengraulis edentulus mantidas sob refrigeração em gelo (0+2°C) foi determinada por parâmetros analíticos físico-químicos, bacteriológicos e sensorial. Nas duas amostras, os teores
Sabrina da Costa Silva Andrade   +6 more
doaj  

An Enzymatic Spectrophotometric Method for the Determination of Xanthine and Hypoxanthine [PDF]

open access: bronze, 1967
James R. Klinenberg   +3 more
openalex   +1 more source

PLK4 is a potential therapeutic target in nonmelanoma skin cancers: Evidence from molecular and in vivo studies

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye   +5 more
wiley   +1 more source

Investigation of the Difference in Growth‐Promoting Factor Secretion Between Canine and Rabbit Corneal Epithelial Cells

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Objective We hypothesized that canine corneal epithelial cells maintain their proliferative properties through autocrine secretion of growth‐promoting factors. This study aimed to investigate the maintenance mechanism of the proliferative properties of canine corneal epithelial cells by comparing the autocrine secretion of soluble factors in ...
Maresuke Morita   +6 more
wiley   +1 more source

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