Cloning, expression, purification and drug targeting of Plasmodium falciparum hypoxanthine guanine xanthine phosphoribosyltransferase (HGXPRT) [PDF]
Includes bibliographical references.The research concerns sub-cloning the gene for HGXPRT from Plasmodium falciparum from a vector with a His-tag facility to one without, expression of the protein in E. coli, and purification.
Mbewe, Boniface
core
Hypoxanthine, a Growth Substance for Phycomyces [PDF]
W J, Robbins, F, Kavanagh
openaire +2 more sources
Evaluation of Serum Inosine, Hypoxanthine, and Carnitine as Ischemia Markers of Heart Disease [PDF]
Introduction: Heart disease (HD) is a major global death cause, with adenosine triphosphate metabolites, carnitine, and other biomarkers aiding in timely detection and disease prediction.
Hossein Nikpour +3 more
doaj
A hypoxanthine (Hx) biosensor based on immobilized xanthine oxidase (XO) as the bio-component was developed and studied for the rapid analysis of fish (sweet water and marine) and goat meat samples. The biosensor was standardized for the determination of Hx in the range of 0.05 to 2 mM.
Anjan Kumar, Basu +3 more
openaire +1 more source
Theoretical study of reaction coordinates from adenine to hypoxanthine [PDF]
J-GLOBAL ID : 200901085417108282In the 1960s, Löwdin proposed a model for base pair mutations in DNA [Rev. Mod. Phys. 1963, 35, 724-732]. It was that tautomerization by double proton transfer(DTP) of base pairs causes transition after replication.
Umesaki, Keisho +7 more
core
Chemistry of Hypoxanthine: Advancement in Derivatization and Drug Development
Heterocyclic compounds, especially nitrogen‐containing ones, have emerged as central focus in organic synthesis, driven by their vast synthetic versatility and functional utility. Hypoxanthine and its derivatives have long intrigued chemists due to their
Kaur, Prabhjot +3 more
core +1 more source
Purine Metabolism Profiling Reveals Distinct Associations of Uric Acid, Xanthine, and Hypoxanthine with Neurological Severity and Functional Outcome After Acute Ischemic Stroke. [PDF]
Roman-Filip I +6 more
europepmc +1 more source
A distinct serum metabolic profile characterizes osteosarcopenia: identifying potential metabolic biomarkers. [PDF]
Gao H +7 more
europepmc +1 more source
Adenosine Deaminase-Mediated Purine Dysfunction Leads to DNA Repair Inhibition and Senescence in Sporadic Amyotrophic Lateral Sclerosis. [PDF]
Hall B +22 more
europepmc +1 more source
Intermittent fasting exacerbates microplastic-induced gut inflammation via Rikenella-mediated regulation of purine metabolism and Th17/Treg balance. [PDF]
Fu R +10 more
europepmc +1 more source

