Results 111 to 120 of about 64,168 (232)

Simultaneous Electrochemical Determination of Uric Acid, Xanthine, and Hypoxanthine Using AgNPs/MIL-101(Cr) Modified Electrode

open access: yesECS Sensors Plus
This paper presents silver nanoparticles supported by the Matérial Institute Lavoisier-101 (AgNPs/MIL-101(Cr)) for electrochemical determination of uric acid (URA), xanthine (XAT), and hypoxanthine (HPX).
Nguyen Quang Man   +10 more
doaj   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

open access: yesPlant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng   +7 more
wiley   +1 more source

One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives

open access: yesChemBioChem, Volume 27, Issue 19, 14 October 2026.
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler   +2 more
wiley   +1 more source

Concentration of hypoxanthine.

open access: yes, 2013
[A] In post-mortem blood from rat corpses over 96 hours. The average ammonia concentration in plasma and the standard deviations from five rats at each time point are shown. [B] In post-mortem blood from pig corpses over 96 hours.
Andrea E. Donaldson (488176)   +1 more
core   +1 more source

E. coli genetically modified for purine nucleobase release promotes butyrate generation and colonic wound healing during DSS insult

open access: yesGut Microbes
The gut microbiota transforms energy stored as undigestible carbohydrates into a remarkable number of metabolites that fuel intestinal bacterial communities and the host tissue.
J. Scott Lee   +7 more
doaj   +1 more source

Can Non-Conventional Blood Biomarkers Improve Running Performance Prediction? A Proof of Concept

open access: yesLife
Conventional measures such as maximal oxygen uptake (V˙O2max), although widely regarded as the gold standard, do not fully capture endurance performance.
Matija Dvorski   +10 more
doaj   +1 more source

Hypoxanthine Promotes Pulmonary Vascular Remodeling and Adenosine Deaminase Is a Therapeutic Target for Pulmonary Hypertension

open access: yesJACC: Basic to Translational Science
Summary: Uric acid metabolism is implicated in the pathogenesis of pulmonary arterial hypertension, wherein the key metabolite hypoxanthine exhibits elevated levels, thereby promoting pulmonary vascular remodeling through facilitation of cell ...
Jun-Zhuo Shi, MS   +16 more
doaj   +1 more source

Establishment and optimization of a novel mouse model of hyperuricemic nephropathy

open access: yesRenal Failure
Hyperuricemia is a metabolic disorder characterized by elevated serum uric acid levels. Soluble urate can activate immune responses, and the excessive accumulation of urate in the kidneys results in hyperuricemic nephropathy (HN). However, the lack of an
Jiamin Wang   +8 more
doaj   +1 more source

The M. tuberculosis purF::Tn mutant requires exogenous hypoxanthine and thiamine for in vitro growth.

open access: yes
Strains were grown in 7H9 supplemented with 60 μM thiamine and 150 μM hypoxanthine, washed with PBS-T, and diluted to OD600 = 0.05 in 7H9 broth (wild-type and purF::Tn), 7H9 with 150 μM hypoxanthine (purF::Tn +hypoxanthine), or 7H9 with 60 μM thiamine ...
Sarah B. Namugenyi (18176930)   +3 more
core   +1 more source

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