Results 91 to 100 of about 64,168 (232)
Plant, Cell &Environment, EarlyView.ABSTRACT Polyamines are key regulators of plant stress responses, yet their contribution to coordinating local immune responses with systemic immunity remains poorly understood. Here, we investigated how spermine (Spm) homeostasis influences local and systemic defence responses in Arabidopsis thaliana following inoculation with Pseudomonas syringae pv.
Jiaqi Zhao +3 more
wiley +1 more source
, 2016 Genetic disorders can arise from single base substitutions in a single gene. A single base substitution for wild type guanine in the twelfth codon of KRAS2 mRNA occurs frequently to initiate lung, pancreatic, and colon cancer.
Fan Wang (135182) +9 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
ChemosensorsElectrochemical biosensors are integrated bio-receptor–transducer devices that convert specific biological interactions into measurable electrical signals.
Totka Dodevska
doaj +1 more source
Glia, Volume 75, Issue 1, January 2027.sox17 is a maternal effect gene impacting microglia and microglia precursor abundance. sox17 mRNA injection timed to maternal contribution rescues abundance. A CRISPR screen reveals f11r.1, gas6, and mpp1 also regulate microglia abundance. ABSTRACT Embryonic development is shaped by maternal and zygotic factors but how the interplay between these ...
Camden A. Spring +4 more
wiley +1 more source
Formation of hypoxanthine from guanine in rat liver extracts
, 1961 The formation of hypoxanthine from guanine in extracts of rat liver has been observed and its mechanism investigated. Evidence is presented indicating that the reduction occurs at the free base level, the pathway involving deamination to xanthine ...
Biswas, B. B., Abrams, Richard
core +1 more source
The development and critical evaluation of an immunoassay for hypoxanthine in biological matrices. [PDF]
, 2018 A classical radioimmunoassay for hypoxanthine was developed and validated. Hypoxanthine, being a low molecular weight compound (M.W. 136.11) is not immunogenic unless first attached to a macromolecule such as a protein.
Roberts, Beverley.
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7-(2'-Deoxy-?-D-ribofuranosyl)hypoxanthine [PDF]
, 1996 The [alpha]-configured N7 analogue of 2'-deoxyinosine [7-(2'-deoxy-[alpha]-D-ribofuranosyl)hypoxanthine, C10H12N4O4] shows the following structural characteristics: (i) the furanose part of the molecule adopts the 2'-endo conformation [pseudorotation ...
Marfurt, J. +17 more
core +1 more source
Disruption of Lactate Metabolism in the Peripheral Nervous System Leads to Motor‐Selective Deficits
Glia, Volume 74, Issue 12, December 2026.To test the importance of lactate metabolism and shuttling between Schwann cells and neurons in the PNS, we selectively knocked out both LDHA and LDHB in motor neurons, sensory neurons, or Schwann cells. ABSTRACT Schwann cells (SCs) myelinate and provide trophic support to axons in the peripheral nervous system (PNS).
A. Joseph Bloom +11 more
wiley +1 more source
, 1998 The inward transport of two purines, adenosine and hypoxanthine, at 37 degrees C by horse erythrocytes was compared. No mediated transport of adenosine was detected in horse erythrocytes, nor was saturable, high-affinity binding of the potent facilitated-
Harris, Roger C., Jarvis, Simon M.
core +1 more source