Results 81 to 90 of about 55,919 (216)
MedComm – Oncology, Volume 5, Issue 3, September 2026.Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
wiley +1 more source
Brain Pathology, Volume 36, Issue 5, September 2026.Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira +19 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 15, 15 August 2026.Inactivation of the Nrf2/Are pathway in AD leads to decreased antioxidant and anti‐inflammatory response and to the accumulation of beta‐amyloid (Aβ) plaques, resulting in cognitive failure. Treatment with Isoeugenol activates Nrf2, reversing these outcomes by promoting antioxidant response in neuronal cells (N2a) and by increasing the anti ...
Ana Silva +14 more
wiley +1 more source
Advanced Science, Volume 13, Issue 46, 17 August 2026.Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun +11 more
wiley +1 more source
Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody
Animal Research and One Health, Volume 4, Issue 3, Page 293-301, August 2026.This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng +7 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 8, August 2026.ABSTRACT Background Cabozantinib (CABO) is currently an essential drug for first‐line and sequential therapy in the treatment of advanced renal cell carcinoma (RCC). Predicting its therapeutic efficacy will enable efficient drug selection and improve the prognosis of patients.
Takanari Sakai +10 more
wiley +1 more source
Microdetermination of hypoxanthine and xanthine [PDF]
Biochemical Journal, 1939 H A, Krebs, A, Orström
openaire +2 more sources
Insights Into the Biological Mechanisms and Multifunctional Health Benefits of Morelloflavone
eFood, Volume 7, Issue 4, August 2026.Morelloflavone (MF), a biflavonoid from Garcinia and related species, exhibits broad human health benefits through antioxidant, anti‐inflammatory, anticancer, and metabolic regulatory effects. This review highlights its molecular mechanisms, biosynthesis, and emerging roles in chronic disease prevention, emphasizing systems biology and machine learning
Yi Liu +4 more
wiley +1 more source
Food FrontiersRecent studies have found that the amount and proportion of meat flavor–related metabolites differ among different parts of muscle, which is partly attributed to their diverse myofiber type composition.
Manting Ma +6 more
doaj +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Isobavachin alleviates HUA‐induced oxidative stress, inflammation, and fibrosis in the kidney and heart, potentially through its dual role in promoting UA excretion and inhibiting NF‐κB signaling and NLRP3 inflammasome activation. ABSTRACT Hyperuricaemia (HUA) is a recognized risk factor for cardiovascular and renal diseases.
Yongmei Li +9 more
wiley +1 more source