Results 161 to 170 of about 92,945 (337)

Utilizing Cordyceps cicadae Mycelium as a Potential Supplement for Alleviating UVB‐Induced Photokeratitis Symptoms In Vivo

open access: yeseFood, Volume 6, Issue 4, August 2025.
Cordyceps cicadae mycelium extracts (CCME) have been reported to exert beneficial effects on ocular diseases. TV, TBUT, and cornea surface indexes were improved with oral CCME intake. Immunohistochemical assays showed that p63 + , PCNA, NF‐κB and COX‐2 expressions decreased in the CCME group than that of the UVB group. The corneas of those treated with
Tsung‐Han Lu   +6 more
wiley   +1 more source

Exploring the Prevention of Lipid Deposition Caused by High‐Fat Diet and Its Mechanism of Action of Rosa roxburghii Fermented Juice Based on Liver Metabolomics and Gut Microbiota

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Rosa roxburghii fermented juice can improve dyslipidaemia by modulating gut microbiota disorders. Rosa roxburghii fermented juice may regulate lipid deposition by increasing metabolites such as choline, L‐Tyrosine, and L‐Phenylalanine in the liver to improve liver metabolic profile.
Duo Meng   +9 more
wiley   +1 more source

Evaluation of the Uricogenic Effect of Hypoxanthine and the Hypoxanthine‐Lowering Process of Shrimp (Metapenaeus ensis)

open access: yesFood Frontiers
One of the main reasons for hyperuricemia is high purine intake and restricting the intake of high purine food is the main management for avoiding hyperuricemia.
Wanqian Sha   +6 more
doaj   +1 more source

Screening of Theaflavins That Inhibit Proliferation of Nasopharyngeal Carcinoma Cells Through Metabolomics Approaches

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
This study investigated the effects of theaflavin‐3,3′‐digallate (TF3) markedly suppresses the proliferation, migration, invasion of nasopharyngeal carcinoma cells while promoting apoptosis in a dose‐dependent manner. Metabolomic profiling identified 584 altered metabolites, revealing key disruptions in ABC transporter activity and amino acid ...
Chunpeng Wan   +8 more
wiley   +1 more source

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

open access: yesAngewandte Chemie, Volume 137, Issue 28, July 7, 2025.
AZD0156, an ATM kinase inhibitor in clinical development, shows promising multistage antiplasmodial activity by targeting Plasmodium falciparum phosphatidylinositol 4‐kinase (PfPI4Kβ). With an improved specificity profile relative to other PfPI4Kβ inhibitors and moderate efficacy in a P.
John G. Woodland   +33 more
wiley   +2 more sources

Subtle Alterations in Hippocampal Neuronal Activity Coincide With Early Sex‐Specific Differences in Amyloidosis and Microglia in a Pre‐Symptomatic Mouse Model of Alzheimer‐Like Pathology

open access: yesGlia, Volume 73, Issue 8, Page 1727-1745, August 2025.
Main Points In a pre‐symptomatic mouse model of Alzheimer disease, despite higher amyloid‐β load females display less plaques than males. More efficient synaptic transmission as well as less microgliosis point to better early coping with pathogenesis in females.
Thomas Chaigneau   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy