Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain [PDF]
core +1 more source
Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley +1 more source
The Diverse Effect of HDAC Inhibitors: Sodium Butyrate and Givinostat on Microglia Polarization After Hypoxia-Ischemia In Vitro. [PDF]
Ziabska K +3 more
europepmc +1 more source
New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
Correction: Jonsdotter et al. MerTK and the Role of Phagoptosis in Neonatal Hypoxia-Ischemia. <i>Cells</i> 2025, <i>14</i>, 1862. [PDF]
Jonsdotter A +6 more
europepmc +1 more source
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape +3 more
wiley +1 more source
[Expression of Concern] PirB restricts neuronal regeneration in developing rat brain following hypoxia‑ischemia. [PDF]
Wang H, Xiong Y, Mu D.
europepmc +1 more source
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee +4 more
wiley +1 more source
Dual-modal metabolic analysis reveals hypothermia-reversible uncoupling of oxidative phosphorylation in neonatal brain hypoxia-ischemia. [PDF]
Sun N +11 more
europepmc +1 more source
Bioactive Magnesium Silicate Activating Myocardial Energy Metabolism For Infarcted Myocardium Repair
ABSTRACT The heart is a highly energy‐dependent organ, developing bioenergy‐activating biomaterials to activate myocardial adenosine triphosphate (ATP) production and restore dysregulated energy homeostasis is a promising solution for its functional recovery.
Zhibin Liao +11 more
wiley +1 more source

