Results 211 to 220 of about 678,452 (368)

Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription. [PDF]

J Biol Chem, 2023
Downes N, Niskanen H, Tomas Bosch V, Taipale M, Godiwala M, Väänänen MA, Turunen TA, Aavik E, Laham-Karam N, Ylä-Herttuala S, Kaikkonen MU.   +10 more
europepmc   +1 more source

The transcription of the alarmin cytokine interleukin-1 alpha is controlled by hypoxia inducible factors 1 and 2 alpha in hypoxic cells [PDF]

, 2012
Peleg Rider, Irena Kaplanov, Marianna Romžová, Liora Bernardis, Alex Braiman, Elena Voronov, Ron N. Apte   +6 more
openalex   +1 more source

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

Proceedings of the National Academy of Sciences of the United States of America, 1997
P. Maxwell, G. Dachs, J. Gleadle, L. Nicholls, A. Harris, I. Stratford, O. Hankinson, C. Pugh, P. Ratcliffe   +8 more
semanticscholar   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Hypoxia-Inducible Factor 1-Alpha [PDF]

, 2020
openaire   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype

, 2014
Lisha Xiang, Daniele M. Gilkes, Hongxia Hu, Naoharu Takano, Weibo Luo, Haiquan Lu, John W. Bullen, Debangshu Samanta, Houjie Liang, Gregg L. Semenza   +9 more
openalex   +2 more sources

Editor's evaluation: Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes

, 2021
Ernestina Schipani
openalex   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Immunohistochemical Expression of Hypoxia-Inducible Factor-1 Alpha in Oral Squamous Cell Carcinoma. [PDF]

Cureus
Thangjam N, Marbaniang E, Dey B, Harris C, Lynser D, Kalita P.   +5 more
europepmc   +1 more source