Results 221 to 230 of about 1,301,346 (361)

Red Blood Cell Membrane‐Camouflaged Red Phosphorus‐Modified C3N4 for Enhanced Tumoral Photodynamic Therapy

Advanced Materials Interfaces, EarlyView.
Photodynamic therapy (PDT) faces clinical challenges due to poor tumor targeting and systemic toxicity. Herein, a biomimetic C3N4‐RP@RBCm nanoplatform is developed via erythrocyte membrane encapsulation, enabling CD47‐mediated immune evasion and EPR‐driven tumor accumulation.
Jiaxiu Liu, Jingying Chen, Tianyang Li, Pingping Meng, Xitong Lin, Yuting Zhai, Yukun Zhu, Daohao Li, Dongjiang Yang, Shuchao Zhang   +9 more
wiley   +1 more source

Mechanisms governing target search and binding dynamics of hypoxia-inducible factors. [PDF]

Elife, 2022
Chen Y, Cattoglio C, Dailey GM, Zhu Q, Tjian R, Darzacq X.   +5 more
europepmc   +1 more source

Expression of hypoxia-inducible factor 1: mechanisms and consequences

, 2000
Gregg L. Semenza
openalex   +1 more source

Expression of hypoxia-inducible factor-1α in oligodendrogliomas [PDF]

, 2001
Peter Birner, Brigitte Gatterbauer, Georg Oberhuber, Monika Schindl, Karl Rössler, A. Prodinger, Herbert Budka, Johannes A. Hainfellner   +7 more
openalex   +1 more source

An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten   +7 more
wiley   +1 more source

A High‐Throughput AngioPlate Platform with Integrated AngioTEER for Modeling and Monitoring Renal Proximal Tubule Injury

Advanced Materials Technologies, EarlyView.
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar, Anushree Chakravarty, Kimia Asadi Jozani, Brenda Truong, Matana Hendrickson, Ahmed Attia, Muna Sabouny, Anna Basatskaya, Sergi Clotet‐Freixas, Madeleine Ludlow, Alexander Sotra, Dawn S. Y. Lin, Feng Zhang, Boyang Zhang   +13 more
wiley   +1 more source

Hypoxia-Inducible Factors and Diabetic Kidney Disease-How Deep Can We Go? [PDF]

Int J Mol Sci, 2022
Stanigut AM, Pana C, Enciu M, Deacu M, Cimpineanu B, Tuta LA.   +5 more
europepmc   +1 more source

Nonhypoxic Pathway Mediates the Induction of Hypoxia-inducible Factor 1α in Vascular Smooth Muscle Cells

, 2000
Darren E. Richard, Edurne Berra, Jacques Pouysségur   +2 more
openalex   +1 more source

HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression [PDF]

, 2001
Erik Laughner, Panthea Taghavi, Kelly A. Chiles, Patrick C. Mahon, Gregg L. Semenza   +4 more
openalex   +1 more source

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.

TIPS - Trends in Pharmacological Sciences, 2012
G. Semenza
semanticscholar   +1 more source